丹皮酚的磺化、产物鉴定及抑菌作用的比较  

The Sulfonation of Paeonol and Survey of Sulfonate and Comparative Study on Bacteriostatic Effects

作　　者：吴晓慧[1] 吴国荣[1] 张卫明[2] 顾龚平[2] 沙莎[1] 王习达[1] 

机构地区：[1]南京师范大学生命科学学院,南京210097 [2]南京野生植物综合利用研究院,南京210042

出　　处：《南京师大学报（自然科学版）》2003年第4期99-102,共4页Journal of Nanjing Normal University(Natural Science Edition)

基　　金：江苏省高校省级重点实验室开放研究课题 (16 4 0 70 30 14 0 2 ) .

摘　　要：以水蒸气蒸馏法从牡丹皮中提取丹皮酚 ;用浓硫酸、发烟硫酸磺化丹皮酚 ,得产物丹皮酚磺酸钠 ,并通过HPLC、TLC、FTIR、UV检测鉴定其理化性质 ;对丹皮酚、丹皮酚磺酸钠进行了初步的抑制植物病原细菌和真菌的试验 ,发现其对稻细条斑病菌 (简称RS10 5 )、青枯病菌、苹果斑枯病菌、玉米纹枯病菌有较强的抑制作用 .Paeonol was extracted from peony by steam distillation. Sodium paeonol sulfonate was synthesized by treating paeonol with concentrated sulfuric acid and oleum,and its physicochemical properties were surveyed by manners of HPLC、TLC、FTIR and UV. Primary bacteriostatic effects on plant pathogenic fungi and bacteria showed that paeonol and sodium paeonol sulfonate had remarkably inhibiting effects on Xanthmonas oryzae pv.oryzicda,Pseudomonas solanacearum Smith, Phyllosticta mali Pril.et Delac.and Rhizoctonia solani Kühn.

关 键 词：丹皮酚 磺化 产物鉴定 抑菌 水蒸气蒸馏法 稻细条斑病菌 青枯病菌 中药材 理化性质鉴定 

分 类 号：R282.5[医药卫生—中药学] Q946.82[医药卫生—中医学]