CT引导下经皮穿刺注射乙醇治疗甲状旁腺腺瘤  

CT-guided percutaneous ethanol ablation of parathyroid adenoma

作　　者：左长京[1] 曲伸[2] 田建明[1] 王培军[1] 林琳[1] 黄祥忠[3] 任方远[1] 郝西彦[1] 

机构地区：[1]第二军医大学长海医院放射科,上海200433 [2]第二军医大学长海医院内分泌科,上海200433 [3]江苏省江阴市人民医院放射科

出　　处：《介入放射学杂志》2003年第2期115-117,共3页Journal of Interventional Radiology

摘　　要：目的　探讨CT引导下经皮穿刺乙醇注射 (PEI)治疗甲状旁腺腺瘤所致甲状旁腺功能亢进的疗效。方法　 1例经活检证实的甲状旁腺腺瘤 ,在CT引导下用 2 2G细针从前外方穿入病灶 ,在病灶多点、分次注射无水乙醇。结果　经过 2次CT引导下PEI治疗 ,6个月后复查CT ,示病灶体积显著缩小、由显著强化转变为无强化 ,治疗结束后 2d至 12个月 ,血甲状旁腺素、血钙、血磷均恢复至正常水平 ,临床症状显著改善。结论　CT引导下PEI治疗甲状旁腺功能亢进症疗效佳、创伤小 。Objective To validate the theraputic efficacy of percutaneous ethanol injection(PEI) for hyperparathyroidism caused by parathyroid adenoma.Methods One case of parathyroid adenoma underwent PEI whose diagnosis was comfirmed by biopsy. The 22 gauge needle was punctured into the adenoma under CT guidance and ethanol was injected into the lesion at multiple points. Results The CT images obtained 6 months after 2 times of CT guided PEI revealed that the volume of the adenoma decreased markedly together obviously with decrease of enhancement after the injection of contrast media. The level of serum parathyroid hormone, calcium and phosphorous returned normal 2 days to 12 months after the management. The clinical manifestations improved markedly.Conclusions CT guided PEI is a minimally invasive and highly effective theraputic modality for hyperparathyroidism. It can serve as an important supplement to surgery.

关 键 词：CT引导 经皮穿刺 甲状旁腺腺瘤 甲状旁腺功能亢进 无水乙醇 

分 类 号：R736.2[医药卫生—肿瘤] R581.1[医药卫生—临床医学]