单克隆抗体治疗单纯疱疹性角膜炎的临床观察  

Clinical Observation of Herpes Keratitis Treatment by Using Monoclonal Antlbodles

作　　者：杨良户[1] 秦克锋[2] 喻启桂[2] 于纯智[1] 高谦 王海涛[2] 郑仁瑞 马吉献[1] 汪美先[2] 姜绍谆[2] 

机构地区：[1]第四军医大学西京医院眼科,西安710032 [2]第四军医大学西京医院分子病毒学研究室,西安710032

出　　处：《眼科研究》1992年第2期105-107,共3页Chinese Ophthalmic Research

摘　　要：应用抗HSV 糖蛋白gC 和gD 的单克隆抗体制成的滴眼液,滴眼治疗单纯疱疹病毒性角膜炎患者共43例46只眼,其中治愈39只眼(84.8%),基本治愈7只眼(15.2%),总有效率为100%.表明局部应用单克隆抗体制剂是治疗单纯疱疹病毒性角膜炎的一条新途径。43 patients (46 eyes) with herpes simplex keratitis (HSK) received the treatment byusing monoclonal antibodies against gC and gD of herpes simplex virus (HSV).39 eyes(84.8%) became completely free of HSK and 7 eyes (15.2%) were much better than before.The effect rate of 100% has been noted.All patients have not relapsed over 3 to 20mouthes.The evidence reported here suggests that it may be a new way to treat HSK byusing monoclonal antibodies.

关 键 词：角膜炎 单克隆抗体 HSK 

分 类 号：R772.21[医药卫生—眼科]