乳酸钠林格注射液细菌内毒素检查方法的考察  

The Bacterial Endotoxin Test for Sodium lactate Ringer’s Injection

作　　者：鱼爱和[1] 刘泉生[1] 张兰华[1] 

机构地区：[1]中国人民解放军261医院药剂科,北京100094

出　　处：《解放军药学学报》2004年第2期136-138,共3页Pharmaceutical Journal of Chinese People's Liberation Army

摘　　要：目的　建立乳酸钠林格注射液 (SLRI)的细菌内毒素检查法。方法　确定乳酸钠林格注射液的细菌内毒素限值 ,并进行干扰试验。结果　乳酸钠林格注射液对细菌内毒素检查无干扰作用 ;检查可选用的鲎试剂灵敏度最小值为 0 .2 5EU·ml-1 。Aim To establish a bacterial endotoxin testing method for Sodium Lactate Ringer’s Injection(SLRI).Methods The limit content of bacterial endotoxin test(BET) and the maximal undisturbed concentration of SLRI were determined.Results SLRI could not disturb the BET.The minimal sensitivity value of tachypleus amebocyte lysate(TAL) is 0.25EU·ml -1 .Conclusion The BET for SLRI can replace the pyrogen test.

关 键 词：乳酸钠林格注射液 细菌内毒素检查 干扰试验 鲎试剂 

分 类 号：R927.1[医药卫生—药学]