多发性脑膜瘤32例报告  

Multiple meningiomas:report of 32 cases

作　　者：张良文[1] 朱树干[1] 吴承远[1] 见文成[1] 李新钢[1] 刘玉光[1] 

机构地区：[1]山东大学齐鲁医院神经外科,济南250012

出　　处：《中华外科杂志》2004年第3期166-168,共3页Chinese Journal of Surgery

摘　　要：目的　探讨多发性脑膜瘤的发生、分类、诊断与治疗。方法　对 32例多发性脑膜瘤患者的临床资料进行回顾性分析研究。结果　 32例多发性脑膜瘤包括原发多发 18例 ,术后多发 7例 ,合并神经纤维瘤病 4例 ,脑膜瘤病 1例 ,合并垂体瘤、合并胶质瘤各 1例。全部采取手术治疗 ,治愈 2 5例 ,好转 7例。结论　各类多发性脑膜瘤的发生学不同 ,雌激素可能在其发生中起重要作用 ;多数患者可一期切除全部肿瘤 ,由于多数患者对多次手术有较好的耐受性 ,不能一期切除的肿瘤应尽可能分期切除 ;Objective To explore the genesis and classification and diagnosis as well as the treatment of multiple meningiomas. Methods Retrospective study of the materials of 32 cases of multiple meningiomas, simultaneously review of the related articles. Results All patients were divided into 5 groups,primary 18 cases,postoperative 7 cases, accompanied by neurofibromatosis (NF) 4 cases,meningiomatosis 1 case, accompanied with other intracranial tumor 2 cases, one with pituitary adenoma and the other with glioma. All the patiens accepted operation, cured 25 cases,improved 7 cases. Conclusions The cytogenesis of different type of multiple meningiomas probably varied. Estrogen may play an important role in the genesis of multiple meningiomas. One stage resection of all the tumors was feasible to most cases and advocated. Most cases had strong tolerance to several times of operation, staging operation was permitted. The prognosis and principle of treatment of different group varied.

关 键 词：多发性脑膜瘤 分类 诊断 治疗 外科手术 神经纤维瘤病 

分 类 号：R739.45[医药卫生—肿瘤]