急性白血病形态学和免疫学及细胞遗传学分型分析  

AN ANALYSIS OF MORPHOLOGIC, IMMUNOLOGIC AND CYTOGENETIC CLASSIFICATION IN CASES WITH ACUTE LEUKEMIA

作　　者：王德炳[1] 邓星明[1] 陈珊珊[1] 丘镜滢[1] 吴平娜[1] 付剑锋[1] 单福香[1] 江滨[1] 史琪[1] 任汉云[1] 刘素贤 陆道培[1] 

机构地区：[1]北京医科大学血液病研究所

出　　处：《北京医科大学学报》1993年第1期1-4,共4页Journal of Peking University(Health Sciences)

摘　　要：本文从形态学、免疫学和细胞遗传学(MIC)三方面系统观察了31例初治成人急性白血病,结果表明,形态学与细胞化学符合率84％,FAB分型与免疫学分型符合率93.5％,FAB分型与MIC分型符合率为96.8％,免疫学分型与MIC分型符合率亦为96.8％。在27例AML中,淋巴细胞抗原阳性(Ly^+-AML)6例,占22.2％。31例急性白血病中染色体核型异常15例,占48.4％。We observed morphologic, immunologic, and cytogenetic classification in 31 untreated adult pati-ents with acute leukemia. It was found the correspondence rate between morphology and cytochemistrywas 84%, the correspondence rate between FAB classification and immunologic classification was93.5%, and the correspondence rate between. immunologic classification and MIC classification was96.8K. Among 27 patients with acute myelogenous leukemia (AML), six cases showed lymphocyteantigen-positive (22.2%). Of 31 cases of acute leukemia, 15 showed chromosome karyotypic abnorma-lities (48.4%). Of 13 cases of AML-M_2, 5 had t(8;21). Of 8 cases of AML-M_3, 3 had t(15; 17).Amnog 4 patients with acute lymphocytic leukemia, one had t(9; 22), one had t(9; 15; 22).

关 键 词：形态学 免疫学 遗传学 白血病 

分 类 号：R733.7[医药卫生—肿瘤]