血竭的超临界CO_2流体萃取工艺研究  

Technology of supercritical CO_2 extraction process of Dragon's Blood

作　　者：俞蔚[1] 雍克岚[1] 

机构地区：[1]上海大学生命科学学院,上海200436

出　　处：《中草药》2004年第6期633-635,共3页Chinese Traditional and Herbal Drugs

基　　金：上海市科技发展基金资助项目 ( 0 2 DZ9118)

摘　　要：目的　研究超临界 CO2 流体萃取 (SFE- CO2 )血竭中抑制α-葡萄糖苷酶有效成分的工艺条件。方法　采用单因素法 ,探讨了压力、温度、时间和 CO2 流量对血竭萃余率和抑制 α-葡萄糖苷酶活力提高率的影响。结果　最佳工艺条件为萃取压力 15 MPa,温度 4 5℃ ,CO2 流量为 30 kg/ h,时间 2 h。优于传统的索氏抽提。结论　 SFE- CO2 工艺用于血竭中有效成分提取 ,萃余率和抑制Object To study the technology of supercritical CO_2 extraction of effective components from Dragon's Blood which has the inhibiting function on α-glucosidase. Methods The influence of the extraction pressure, temperature, time and fluid velocity on surplus extraction rate and the improvement of inhibition was mainly discussed. Results The optimal experimental parameters were 15 MPa extraction pressure, 45 ℃ extraction temperature, 30 kg/h fluid velocity and 2 h extraction time. Conclusion The results show that SFE-CO_2 can enormously increase the surplus extraction rate and the inhibitory activities on α-glucosidase.

关 键 词：血竭 Α-葡萄糖苷酶 超临界CO2萃取 

分 类 号：R284.2[医药卫生—中药学] R286.02[医药卫生—中医学]