肿瘤预后相关免疫抑制分子概述  

The Overview of Tumor-Related Immunosuppressive Molecules

作　　者：张冬云[1] 刘冉[2] 刘安丽[1] 李寅[1] 王静[1] 

机构地区：[1]南阳医学高等专科学校,基础医学部,河南南阳 [2]南阳医学高等专科学校,第一附属医院肿瘤科,河南南阳

出　　处：《临床医学进展》2015年第2期78-83,共6页Advances in Clinical Medicine

摘　　要：肿瘤机体内免疫抑制细胞、免疫抑制分子状态与肿瘤发生、发展密切相关。本文综述了肿瘤免疫过程中参与肿瘤免疫逃逸的免疫抑制分子PD-1,CTLA-4,TIM-3,LAG-3,CD160,BTLA的功能状况及最新研究进展。Tumorigenesis was closely related to the states of immune tumor suppressor cells and immuno-suppressive molecules. In the paper, we overviewed current functional situation and newly re-search progress of immunosuppressive molecules, e.g. programmed death-1, cytotoxic T lympho-cyte-associated antigen-4, T cell immunoglobulin domain and mucin domain-3, B and T lymphocyte attenuator, LAG-3, CD160, which took part in the tumor immune escape in the process of tumor immunity.

关 键 词：肿瘤 免疫 免疫抑制分子 综述 

分 类 号：R73[医药卫生—肿瘤]