散发型克雅病2例并文献复习  

Two Cases Report of Sporadic Creutzfeldt-Jakob Disease and Literature Re-view

作　　者：张娇娇 马爱军[1] 

机构地区：[1]青岛大学附属医院神经内科,山东 青岛

出　　处：《临床医学进展》2024年第3期66-72,共7页Advances in Clinical Medicine

摘　　要：目的:探讨克雅病临床特征及诊断。方法:通过对2例克雅病患者的临床表现、诊断、辅助检查等进行分析,并进行文献复习。结果:克雅病症状不典型,结合患者症状及MR“花边征”及脑脊液14-3-3蛋白做出诊断。结论:克雅病诊断困难,目前尚无有效治疗手段,且预后极差,应被临床医生所重视。Objective: To investigate the clinical features and diagnosis of Creutzfeldt-Jakob disease. Methods: The clinical manifestations, diagnosis and auxiliary examination of two patients with Creutz-feldt-Jakob disease were analyzed and literature review was conducted. Results: The symptoms of Creutzfeldt-Jakob disease were atypical, and the diagnosis was made based on the patient’s symp-toms and MR “lace sign” and cerebrospinal fluid 14-3-3 protein. Conclusion: The diagnosis of Creutzfeldt-Jakob disease is difficult, there is no effective treatment method, and the prognosis is very poor, which should be paid attention to by clinicians.

关 键 词：克雅病 朊病毒病 病例报告 

分 类 号：R73[医药卫生—肿瘤]