生物催化法生产2-苯乙醇的研究现状  

The Study of Biotechnological Production of 2-Phenylethanol

作　　者：曹明乐[2] 姜兴林[1] 张海波[1] 咸漠[1] 黄峰[2] 

机构地区：[1]中国科学院青岛生物能源与过程研究所,青岛 [2]山东大学微生物技术国家重点实验室,济南

出　　处：《生物过程》2012年第2期89-97,共9页Bioprocess

摘　　要：2-苯乙醇(2-Phenylethanol)也叫β-苯乙醇,英文简称2-PE,具有淡雅、细腻、持久、玫瑰香味的芳香族香气物质。2-苯乙醇可以作为香料广泛应用于香水、化妆品、食品等行业,此外2-苯乙醇在医药中间体及精细化工等行业也有重要的开发价值。目前2-苯乙醇主要是通过化学方法合成,生物催化法具有能耗低、环境污染小及人们对“天然”产品的要求也越来越高使得生物催化法来合成“天然”的2-苯乙醇受到越来越多的重视。本综述主要介绍了2-苯乙醇的合成现状,并且着重对生物合成方法、代谢途径及当前发酵方法优缺点进行了论述。2-Phenylethanol (β-Phenylethanol) is aromatic flavour and fragrance compound with an elegant, fine, endure, rose-like odour. It can be used as additives in perfume, cosmetic, food industries. It also can be used as pharmaceutical intermediates and fine chemicals. So far, 2-PE is mainly produced chemically. The biosynthesis of 2-PE is receiving more attentions, because of its low energy consumption, environmentally friendly, and the demand for the “natural” 2-PE. This review introduces the production of 2-PE especially the biosynthesis method, metabolic pathway, and fermentation method.

关 键 词：2-苯乙醇 香料 生物催化 艾利氏途径 原位萃取 

分 类 号：TQ2[化学工程—有机化工]