基于“伏邪理论”探讨溃疡性结肠炎复发之证治特点  

Discussion on Treatment Characteristics of Recurrence of Ulcerative Colitis Based on “The Theory of Hidden Pathogens”

作　　者：郑晗月 

机构地区：[1]成都中医药大学临床医学院,四川 成都

出　　处：《中医学》2025年第2期583-587,共5页Traditional Chinese Medicine

摘　　要：溃疡性结肠炎(ulcerative colitis, UC)是一种病因尚未阐明、发病机制复杂的慢性炎症性疾病,因其具有周期性、反复发作、西药治疗不良反应多等特点,也是消化系统常见的难治性疾病,而中医药在该病的治疗上具有独特优势。文章以伏邪理论入手,探讨溃疡性结肠炎反复发作的病因病机与发病特点,总结出其根本病因病机为正气虚衰,邪气伏留,阻碍气机,扰乱气血,进一步发为湿毒、瘀血等病理产物,也进一步加剧“炎–癌”转化。治疗上应以健脾益气、清化湿热、活血化瘀、升清降浊为主,同时治疗过程需把握攻补时机,内外治结合,身心同治,以期为中医药在溃疡性结肠炎的预防、治疗、防复发及转移上提供新思路,提高临床疗效。Ulcerative colitis is a chronic inflammatory disease characterized by unexplained etiology and complex pathogenesis, and it is also a common intractable disease of the digestive system due to its periodic nature, frequent relapses, and the numerous adverse reactions associated with Western medical treatments. Traditional Chinese medicine (TCM) offers distinct advantages in the treatment of this disease. Grounded in the theory of hidden pathogens, this paper explores the etiology, pathogenesis, and recurrent characteristics of ulcerative colitis, and concludes that the etiological and pathogenic factors of ulcerative colitis are the deficiency of healthy qi, the persistence of evil qi, the stagnation of qi, the disturbance of qi and blood, which make the subsequent development of dampness and blood stasis, which exacerbate the transformation of the “inflammation-to-cancer”. Treatment should focus on strengthening the spleen, clearing heat and promoting dampness, promoting blood and resolving stasis, and ascending lucidity and descending turbidity. Additionally, the treatment process should seize the timing of attacking and supplementing, combining internal and external treatments, and treating both physi

关 键 词：溃疡性结肠炎 伏邪理论 湿热瘀血 脾虚 

分 类 号：R57[医药卫生—消化系统]