Malignant Peripheral Nerve Sheath Tumor of the Thigh Invading the Superficial Femoral Artery, with Necrotic Lung Metastases as Presenting Symptoms  

作　　者：Patrick Mailleux François Buche Geoffrey Colin Patrick Mailleux;François Buche;Geoffrey Colin(Department of Imaging, Clinique Bouge, Bouge, Belgium;Department of Vascular Surgery, Clinique St Luc, Bouge, Belgium)

机构地区：[1]Department of Imaging, Clinique Bouge, Bouge, Belgium [2]Department of Vascular Surgery, Clinique St Luc, Bouge, Belgium

出　　处：《Advances in Lung Cancer》2020年第2期24-29,共6页肺癌（英文）

摘　　要：A NF1 (neurofibromatosis 1) patient developed multiple necrotic lung metastases</span><span style="font-family:Verdana;"> from a sciatic malignant peripheral nerve sheath tumor (MPNST) invading the superficial femoral artery. The first diagnosis was metastases of a non-small-cell adenocarcinoma because the right calf MPNST was not clinical</span><span style="font-family:Verdana;">ly noticeable ant that the chest/abdomen PET/CT did not include the region of the legs. When the MPNST was diagnosed, new histological analysis on the </span><span style="font-family:Verdana;">metastases changed the diagnosis to that of epithelioid undifferentiated sarcoma.</span><span style="font-family:Verdana;"> The article deals with the sometimes-delayed diagnosis in those NF1 patients </span><span style="font-family:Verdana;">with large palpable masses and chronic pain pre-existing the malignant transformat</span><span style="font-family:Verdana;">ion, and discusses the difficulty of the biopsy of necrotic metastases.A NF1 (neurofibromatosis 1) patient developed multiple necrotic lung metastases</span><span style="font-family:Verdana;"> from a sciatic malignant peripheral nerve sheath tumor (MPNST) invading the superficial femoral artery. The first diagnosis was metastases of a non-small-cell adenocarcinoma because the right calf MPNST was not clinical</span><span style="font-family:Verdana;">ly noticeable ant that the chest/abdomen PET/CT did not include the region of the legs. When the MPNST was diagnosed, new histological analysis on the </span><span style="font-family:Verdana;">metastases changed the diagnosis to that of epithelioid undifferentiated sarcoma.</span><span style="font-family:Verdana;"> The article deals with the sometimes-delayed diagnosis in those NF1 patients </span><span style="font-family:Verdana;">with large palpable masses and chronic pain pre-existing the malignant transformat</span><span style="font-family:Verdana;">ion, and discusses the difficulty of the biopsy of necrotic metastases.

关 键 词：Necrotic Metastasis Malignant Peripheral Nerve Sheath Tumor NF1 Lung Adenocarcinoma ¹⁸F-FDG PET/CT Unknown Primary Tumor 

分 类 号：R73[医药卫生—肿瘤]