Salivary Duct Carcinoma of the Parotid Gland Definitively Diagnosed by Immunohistochemical Examination of Pulmonary Metastases  

作　　者：Mei Yonemoto Kojiro Onizawa Kenji Yamagata Shogo Hasegawa Toru Yanagawa Hiroki Bukawa 

机构地区：[1]Department of Oral and Maxillofacial Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan

出　　处：《Case Reports in Clinical Medicine》2014年第3期118-121,共4页临床医学病理报告（英文）

摘　　要：Salivary duct carcinoma (SDC) is a rare, high-grade, aggressive malignancy, as having a morphologic resemblance to ductal carcinoma of the breast. We present here an atypical SDC of the parotid gland in a 63-year-old man that was diagnosed from immunohistochemical findings. The immunohistochemistry was similar in the parotid lesion and pulmonary metastases in autopsy specimens, but only the latter showed a cribriform pattern and comedolike necrosis. Although the parotid tumor was treated with concurrent chemoradiotherapy and adjuvant chemotherapy for over 21 months, the patient died of respiratory failure caused by advanced pulmonary metastases.Salivary duct carcinoma (SDC) is a rare, high-grade, aggressive malignancy, as having a morphologic resemblance to ductal carcinoma of the breast. We present here an atypical SDC of the parotid gland in a 63-year-old man that was diagnosed from immunohistochemical findings. The immunohistochemistry was similar in the parotid lesion and pulmonary metastases in autopsy specimens, but only the latter showed a cribriform pattern and comedolike necrosis. Although the parotid tumor was treated with concurrent chemoradiotherapy and adjuvant chemotherapy for over 21 months, the patient died of respiratory failure caused by advanced pulmonary metastases.

关 键 词：SALIVARY Duct Carcinoma (SDC) Immunohistochemistry PAROTID Tumor Pulmonary METASTASES AUTOPSY 

分 类 号：R73[医药卫生—肿瘤]