Magnusiomyces capitatus in Immune-Competent Patients with Pulmonary Haemorrhage and Systemic Lupus Erythematosus  

作　　者：Waleed Amasaib Ahmed Angham Ahmed Almakki Abeer Ahmed Bashinim Abdelgaffar A. Mohamed Amna Al Kalkami Mohannad AbuRageila Waleed Amasaib Ahmed;Angham Ahmed Almakki;Abeer Ahmed Bashinim;Abdelgaffar A. Mohamed;Amna Al Kalkami;Mohannad AbuRageila(Department of Medicine, Security Forces Hospital, Makkah, Saudi Arabia;Department of Laboratory and Blood Bank, Security Forces Hospital, Makkah, Saudi Arabia;Department of Critical Care, Security Forces Hospital, Makkah, Saudi Arabia)

机构地区：[1]Department of Medicine, Security Forces Hospital, Makkah, Saudi Arabia [2]Department of Laboratory and Blood Bank, Security Forces Hospital, Makkah, Saudi Arabia [3]Department of Critical Care, Security Forces Hospital, Makkah, Saudi Arabia

出　　处：《Case Reports in Clinical Medicine》2023年第10期408-417,共10页临床医学病理报告（英文）

摘　　要：Invasive fungal infections have grown significantly over the last two decades, owing to an increase in immunocompromised hosts and geriatric patients. When the host’s defenses are compromised, such infections are associated with severe morbidity and mortality. Here, a rare case of fungal infection in a 61-year-old immunocompetent male patient from Saudi Arabia was reported, who suffered from pulmonary hemorrhage and Systemic Lupus Erythematous. Bronchoalveolar Lavage was used as a diagnostic tool to identify the fungus reported in the case. The pathogenic fungal specie identified as Magnusiomyces capitatus, in macroscopic and microscopic morphological characteristics of the colonies. Based on clinical evidence, liposomal amphotericin formulation was recommended for initial therapy against fungal infection. Also, liposomal amphotericin B induced mycological eradication up to 70 percent in patients with proven Magnusiomyces capitatus infection. In addition to addressing suspected Systemic lupus erythematosus, the patient’s health has improved with no evidence of pulmonary bleeding and hemoptysis.Invasive fungal infections have grown significantly over the last two decades, owing to an increase in immunocompromised hosts and geriatric patients. When the host’s defenses are compromised, such infections are associated with severe morbidity and mortality. Here, a rare case of fungal infection in a 61-year-old immunocompetent male patient from Saudi Arabia was reported, who suffered from pulmonary hemorrhage and Systemic Lupus Erythematous. Bronchoalveolar Lavage was used as a diagnostic tool to identify the fungus reported in the case. The pathogenic fungal specie identified as Magnusiomyces capitatus, in macroscopic and microscopic morphological characteristics of the colonies. Based on clinical evidence, liposomal amphotericin formulation was recommended for initial therapy against fungal infection. Also, liposomal amphotericin B induced mycological eradication up to 70 percent in patients with proven Magnusiomyces capitatus infection. In addition to addressing suspected Systemic lupus erythematosus, the patient’s health has improved with no evidence of pulmonary bleeding and hemoptysis.

关 键 词：Magnusiomyces capitatus Fungal Infection Bronchoalveolar Lavage Pulmonary Haemorrhage SLE (Systemic Lupus Erythematosus) AMPHOTERICIN A Case Report 

分 类 号：R57[医药卫生—消化系统]