Volatile Compounds Analysis of Tunisian Propolis and Its Antifungal Activity  

作　　者：Ayari Jihene Ines Jabri Karoui Ayed Ameni Majdi Hammami Manef Abderrabba 

机构地区：[1]Laboratoire Matériaux Molécules et Applications, Institut Préparatoire des Etudes Scientifiques et Techniques, IPEST, La Marsa, Tunisia [2]Laboratoire des Substances Bioactives, Centre de Biotechnologie’a la Technopole de Borj-Cedria (CBBC), Hammam-Lif, Tunisia

出　　处：《Journal of Biosciences and Medicines》2018年第6期115-131,共17页生物科学与医学（英文）

摘　　要：In this study, four samples of Tunisian propolis were analyzed for their volatile compounds. Static Headspace technique coupled with gas chromatography-mass spectrometry (GC/MS) was used for the volatile profile characterization. Statistical investigation of the samples was made applying hierarchical clustering method, K-Means cluster and principal component analysis. Results showed that 47, 36, 30 and 24 different compounds were identified, respectively, in the samples from Zouarine, Zelligua, Bizerte and Beni Khalled. Propolis volatiles were dominated by monoterpene hydrocarbons. α-pinene was the major compound representing 81.14%, 82.67% and 90.74%, respectively, of the total propolis volatiles collected from Zelligua, Beni Khalled and Zouarine and only 45.22% of the sample from Bizerte which had a very different composition. The in vitro antifungal activity of the volatiles from all samples against Candida albicans was also assayed and reported.In this study, four samples of Tunisian propolis were analyzed for their volatile compounds. Static Headspace technique coupled with gas chromatography-mass spectrometry (GC/MS) was used for the volatile profile characterization. Statistical investigation of the samples was made applying hierarchical clustering method, K-Means cluster and principal component analysis. Results showed that 47, 36, 30 and 24 different compounds were identified, respectively, in the samples from Zouarine, Zelligua, Bizerte and Beni Khalled. Propolis volatiles were dominated by monoterpene hydrocarbons. α-pinene was the major compound representing 81.14%, 82.67% and 90.74%, respectively, of the total propolis volatiles collected from Zelligua, Beni Khalled and Zouarine and only 45.22% of the sample from Bizerte which had a very different composition. The in vitro antifungal activity of the volatiles from all samples against Candida albicans was also assayed and reported.

关 键 词：PROPOLIS Headspace/GC-MS Α-PINENE PCA ANTIFUNGAL ACTIVITY 

分 类 号：R73[医药卫生—肿瘤]