Anesthetic Management of a Parturient with Thalidomide Phocomelia  

作　　者：Samuel N. Blacker Tiffany E. Angelo 

机构地区：[1]Department of Anesthesiology, Walter Reed National Military Medical Center, Bethesda, MD, USA. [2]Department of Anesthesiology, Womack Army Medical Center, Fort Bragg, NC, USA

出　　处：《Open Journal of Anesthesiology》2012年第3期59-61,共3页麻醉学期刊（英文）

摘　　要：The teratogenicity of thalidomide has been known since the early 1960s [1]. Thalidomide is currently used world wide, including the United States, to treat erythema nodosum leprosum, multiple myeloma, refractory Crohn’s disease, aphthous stomatitis and HIV wasting syndrome. New cases of thalidomide phocomelia are being reported as well. We report a case of the anesthetic challenges of a 23 year-old parturient with thalidomide phocomelia and review the important anesthetic challenges it presents. Spontaneous vaginal delivery under continuous lumbar epidural was achieved in this challenging patient. However, it required careful planning for reliable intravenous access and the use of magnetic resonance imaging (MRI) of her pelvis and lumbar spine.The teratogenicity of thalidomide has been known since the early 1960s [1]. Thalidomide is currently used world wide, including the United States, to treat erythema nodosum leprosum, multiple myeloma, refractory Crohn’s disease, aphthous stomatitis and HIV wasting syndrome. New cases of thalidomide phocomelia are being reported as well. We report a case of the anesthetic challenges of a 23 year-old parturient with thalidomide phocomelia and review the important anesthetic challenges it presents. Spontaneous vaginal delivery under continuous lumbar epidural was achieved in this challenging patient. However, it required careful planning for reliable intravenous access and the use of magnetic resonance imaging (MRI) of her pelvis and lumbar spine.

关 键 词：ANESTHESIA THALIDOMIDE PHOCOMELIA Obstertric ANESTHESIA 

分 类 号：R73[医药卫生—肿瘤]