Ulcerative Colitis in Sub-Saharan Africa: Analysis of 24 Cases in Dakar (Senegal)  

作　　者：Mamadou Ngoné Gueye Sokhna Niang Diop Salamata Diallo Gnagna Diouf Cheikh Ahmadou Bamba Cissé Marème Polèle Fall Mame Aissé Thioubou Marie Louise Bassène Daouda Dia Mouhamadou Mbengue Mamadou Ngoné Gueye;Sokhna Niang Diop;Salamata Diallo;Gnagna Diouf;Cheikh Ahmadou Bamba Cissé;Marème Polèle Fall;Mame Aissé Thioubou;Marie Louise Bassène;Daouda Dia;Mouhamadou Mbengue(Department of Gastroenterology, Idrissa Pouye General Hospital (Former Grand Yoff General Hospital), Dakar, Senegal;Cheikh Anta Diop University, Dakar, Senegal;Department of Gastroenterology, Aristide Le Dantec Hospital, Dakar, Senegal;Department of Gastroenterology, Peace Hospital, Ziguinchor, Senegal)

机构地区：[1]Department of Gastroenterology, Idrissa Pouye General Hospital (Former Grand Yoff General Hospital), Dakar, Senegal [2]Cheikh Anta Diop University, Dakar, Senegal [3]Department of Gastroenterology, Aristide Le Dantec Hospital, Dakar, Senegal [4]Department of Gastroenterology, Peace Hospital, Ziguinchor, Senegal

出　　处：《Open Journal of Gastroenterology》2020年第6期128-136,共9页肠胃病学期刊（英文）

摘　　要：<b><span style="font-family:Verdana;">Introduction: </span></b><span style="font-family:""><span style="font-family:Verdana;">The aim of our study was to determine the socio-demographic</span><span style="font-family:Verdana;">, diagnostic and therapeutic aspects of ulcerative colitis (UC) in one of the larges</span><span style="font-family:Verdana;">t gastroenterology departments in Senegal. </span><b><span style="font-family:Verdana;">Patients and Method: </span></b><span style="font-family:Verdana;">This was a retrospective and descriptive study based on the analysis of the records of patients hospitalized in the Hepato-Gastroenterology Department of the Grand Yoff General Hospital (Dakar, Senegal) between January 2013 and December 2019. All cases of UC were collected. Clinical, biological, endoscopic and his</span><span><span style="font-family:Verdana;">tological data were collected, as well as treatment options. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">We o</span></span><span style="font-family:Verdana;">bserved 24 cases, representing a prevalence of 0.87% of inpatients. The mean </span><span style="font-family:Verdana;">a</span><span style="font-family:Verdana;">ge of patients was 36 (ranged 18 to 73) and sex ratio 0.9 (1</span></span><span style="font-family:Verdana;">3</span><span style="font-family:Verdana;"> females). The</span><span style="font-family:Verdana;"> mean</span><span style="font-family:""><span style="font-family:Verdana;"> diagnostic delay was 1.6 years (ranged 4 months to 5 years). The clinical </span><span style="font-family:Verdana;">symptomatology was dominated by diarrhea with blood and mucus (18 cases). </span><span style="font-family:Verdana;">The Litchiger score on admission averaged 8 and 5 patients (20.8%) had se</span><span style="font-family:Verdana;">vere acute colitis. Colonoscopy showed pancolonic involvement (Montreal E3) in 11 cases (45.8%) and severe endoscopic lesions (stage 3 of the Mayo endosc</span><span styl<b><span style="font-family:Verdana;">Introduction: </span></b><span style="font-family:""><span style="font-family:Verdana;">The aim of our study was to determine the socio-demographic</span><span style="font-family:Verdana;">, diagnostic and therapeutic aspects of ulcerative colitis (UC) in one of the larges</span><span style="font-family:Verdana;">t gastroenterology departments in Senegal. </span><b><span style="font-family:Verdana;">Patients and Method: </span></b><span style="font-family:Verdana;">This was a retrospective and descriptive study based on the analysis of the records of patients hospitalized in the Hepato-Gastroenterology Department of the Grand Yoff General Hospital (Dakar, Senegal) between January 2013 and December 2019. All cases of UC were collected. Clinical, biological, endoscopic and his</span><span><span style="font-family:Verdana;">tological data were collected, as well as treatment options. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">We o</span></span><span style="font-family:Verdana;">bserved 24 cases, representing a prevalence of 0.87% of inpatients. The mean </span><span style="font-family:Verdana;">a</span><span style="font-family:Verdana;">ge of patients was 36 (ranged 18 to 73) and sex ratio 0.9 (1</span></span><span style="font-family:Verdana;">3</span><span style="font-family:Verdana;"> females). The</span><span style="font-family:Verdana;"> mean</span><span style="font-family:""><span style="font-family:Verdana;"> diagnostic delay was 1.6 years (ranged 4 months to 5 years). The clinical </span><span style="font-family:Verdana;">symptomatology was dominated by diarrhea with blood and mucus (18 cases). </span><span style="font-family:Verdana;">The Litchiger score on admission averaged 8 and 5 patients (20.8%) had se</span><span style="font-family:Verdana;">vere acute colitis. Colonoscopy showed pancolonic involvement (Montreal E3) in 11 cases (45.8%) and severe endoscopic lesions (stage 3 of the Mayo endosc</span><span styl

关 键 词：Ulcerative Colitis Sub-Saharan Africa Toxic Megacolon 5 ASA AZATHIOPRINE 

分 类 号：R57[医药卫生—消化系统]