Portal Thrombosis: Clinical, Etiological and Therapeutic Aspects in the Hepato-Gastroenterology Department of the Aristide Le Dantec Hospital in Dakar (Senegal)  

作　　者：Salamata Diallo Coumba Ndaw Diagne Marie Louise Bassène Mamadou Ngoné Gueye Mariéme Polele Fall Mame Aissé Thioubou Cheikh Ahmadou Bamba Cissé Daouda Dia Salamata Diallo;Coumba Ndaw Diagne;Marie Louise Bassène;Mamadou Ngoné Gueye;Mariéme Polele Fall;Mame Aissé Thioubou;Cheikh Ahmadou Bamba Cissé;Daouda Dia(Hôpital Aristide Le Dantec Dakar Sénégal, Dakar, Senegal;Hôpital Idrissa Pouye Dakar Sénégal, Dakar, Senegal;Hôpital de la paix Ziguinchor Sénégal, Dakar, Senegal)

机构地区：[1]Hôpital Aristide Le Dantec Dakar Sénégal, Dakar, Senegal [2]Hôpital Idrissa Pouye Dakar Sénégal, Dakar, Senegal [3]Hôpital de la paix Ziguinchor Sénégal, Dakar, Senegal

出　　处：《Open Journal of Gastroenterology》2021年第11期220-229,共10页肠胃病学期刊（英文）

摘　　要：<strong>Background:</strong> <span><span><span style="font-family:;" "="">Portal thrombosis (PT) is a rare pathology. Its prevalence is es<span>timated at 1%. Its consequences depend on the acute or chronic nature, the extent of the clot and the etiology. In Sub-Saharan Africa, very few studies have been devoted to it.<b> Patients and Method: </b>The objective of our work was to determine the prevalence of PT and to describe its clinical and etiological presentation as well as its therapeutic management in the Hepa</span>to-gastroenterology department of the Aristide Le Dantec hospital in Dakar. This was a retrospective, longitudinal and descriptive study during the period from January 1, 2012, to December 31, 2018. It included all patients followed in ambulatory or inpatient, who presented a PT objectively determined by a medical imaging examination (ultrasound and/or CT scan). Age, gender, clinical and radiological aspects, proposed treatments and etiology of PT were collected. <b>Results: </b>We collected 71 observations. The prevalence of PT was 1.9%. The mean age of the patients was 41 years 15 and 75 years. A predominance of men was found with a sex ratio of 2.73. The clinical manifestations were dominated by abdominal pain (74.6%), ascites (35.7%) and gastrointestinal bleeding (25.4%). Imaging allowed the diagnosis to be made in 50 patients on ultrasound and 21 patients on abdominal CT scan. PT was acute in 5 patients and chronic in 66 patients. Thrombosis was complete in 71.4% of cases and extended to the spleno-mesaraic venous trunk and the superior mesenteric vein in 2.8% and 8.4% respectively. Etiological research found cirrhosis complicated by hepatocellular carcinoma in 67.6% of cases, cirrhosis with cruoric thrombosis in 21.1% of cases, a combined protein C and S deficiency in 1.4% of cases. No aetiology was objectified in 9.9% of cases. Treatment with beta-blockers was initiated in 32 patients. Anticoagulant treatment was performed in one patient. Evolutionarily, no recurrence of bleeding was noted<strong>Background:</strong> <span><span><span style="font-family:;" "="">Portal thrombosis (PT) is a rare pathology. Its prevalence is es<span>timated at 1%. Its consequences depend on the acute or chronic nature, the extent of the clot and the etiology. In Sub-Saharan Africa, very few studies have been devoted to it.<b> Patients and Method: </b>The objective of our work was to determine the prevalence of PT and to describe its clinical and etiological presentation as well as its therapeutic management in the Hepa</span>to-gastroenterology department of the Aristide Le Dantec hospital in Dakar. This was a retrospective, longitudinal and descriptive study during the period from January 1, 2012, to December 31, 2018. It included all patients followed in ambulatory or inpatient, who presented a PT objectively determined by a medical imaging examination (ultrasound and/or CT scan). Age, gender, clinical and radiological aspects, proposed treatments and etiology of PT were collected. <b>Results: </b>We collected 71 observations. The prevalence of PT was 1.9%. The mean age of the patients was 41 years 15 and 75 years. A predominance of men was found with a sex ratio of 2.73. The clinical manifestations were dominated by abdominal pain (74.6%), ascites (35.7%) and gastrointestinal bleeding (25.4%). Imaging allowed the diagnosis to be made in 50 patients on ultrasound and 21 patients on abdominal CT scan. PT was acute in 5 patients and chronic in 66 patients. Thrombosis was complete in 71.4% of cases and extended to the spleno-mesaraic venous trunk and the superior mesenteric vein in 2.8% and 8.4% respectively. Etiological research found cirrhosis complicated by hepatocellular carcinoma in 67.6% of cases, cirrhosis with cruoric thrombosis in 21.1% of cases, a combined protein C and S deficiency in 1.4% of cases. No aetiology was objectified in 9.9% of cases. Treatment with beta-blockers was initiated in 32 patients. Anticoagulant treatment was performed in one patient. Evolutionarily, no recurrence of bleeding was noted

关 键 词：Portal Thrombosis CIRRHOSIS Portal Hypertension 

分 类 号：R57[医药卫生—消化系统]