Risk Factors Recurrence of Spontaneous Ascitic Fluid Infection (Slai) in Cirrhotic Patients  

作　　者：Diallo Mamadou Sarifou Ottou Onana Christian Lionel Soro Dramane Youssouf Oumarou Yaogo Abdoulatif Lohoues-Kouacou Marie Jeanne Diallo Mamadou Sarifou;Ottou Onana Christian Lionel;Soro Dramane;Youssouf Oumarou;Yaogo Abdoulatif;Lohoues-Kouacou Marie Jeanne(Hepato-Gastroenterology Department, The Donka National Hospital, Conakry, Guinea;Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University, Conakry, Guinea;Hepato Gastroenterology Department, Cocody University Hospital, Abidjan, Ivory Coast;Community University Hospital Center of Bangui, Internal Medicine Department, Bangui, African;Hepato Gastroenterology Department, Angr University Hospital, Abidjan, Ivory Coast)

机构地区：[1]Hepato-Gastroenterology Department, The Donka National Hospital, Conakry, Guinea [2]Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University, Conakry, Guinea [3]Hepato Gastroenterology Department, Cocody University Hospital, Abidjan, Ivory Coast [4]Community University Hospital Center of Bangui, Internal Medicine Department, Bangui, African [5]Hepato Gastroenterology Department, Angr University Hospital, Abidjan, Ivory Coast

出　　处：《Open Journal of Gastroenterology》2024年第8期249-260,共12页肠胃病学期刊（英文）

摘　　要：Introduction: After an episode of spontaneous infection of ascitic fluid (ISLA). The recurrence of ISLA at one year is greater than 70%. We studied the risk factors associated with the occurrence of recurrence. Patients and methods: this was a retrospective, descriptive and analytical study of patient files, hospitalized in the department for 12 months, the choice of the sample was of convenience. Results: We have 1347 patient files collected including 389 cases of cirrhosis. We had 37 files of cirrhotic patients with ISLA including 28 cures without recurrence of ISLA, 08 files of patients with recurrence of ISLA and 03 excluded, i.e. a hospital prevalence of recurrence of 0.6% and a prevalence in cirrhotic patients of 23.5%. The most common antecedents were: hospital contact recent (35.3%), the concept of iterative ascites punctures (32.3%), the presence of HCC (29.4%), hepatic encephalopathy (20.6%) and digestive hemorrhage (14.7%). In univariate analysis, recent digestive bleeding was associated with an increased risk of recurrence (OR 7.2, 95% CI 0.96 - 67.1). HBV (62.5%) is the main etiology of cirrhosis. The PNN rate at 250 - 499 mm3 (62.5%), the protein level 3 (75%). Patients on secondary prophylaxis with NORFLOXACIN were 25%. Recurrence of ISLA was treated with CEFTRIAXONE 2 g/24 hours. Conclusion: Recurrence of ISLA is serious, the predictive factors for recurrence are, hospital contact recent, the concept of iterative ascites punctures, the presence of HCC, the presence of hepatic encephalopathy and digestive bleeding.Introduction: After an episode of spontaneous infection of ascitic fluid (ISLA). The recurrence of ISLA at one year is greater than 70%. We studied the risk factors associated with the occurrence of recurrence. Patients and methods: this was a retrospective, descriptive and analytical study of patient files, hospitalized in the department for 12 months, the choice of the sample was of convenience. Results: We have 1347 patient files collected including 389 cases of cirrhosis. We had 37 files of cirrhotic patients with ISLA including 28 cures without recurrence of ISLA, 08 files of patients with recurrence of ISLA and 03 excluded, i.e. a hospital prevalence of recurrence of 0.6% and a prevalence in cirrhotic patients of 23.5%. The most common antecedents were: hospital contact recent (35.3%), the concept of iterative ascites punctures (32.3%), the presence of HCC (29.4%), hepatic encephalopathy (20.6%) and digestive hemorrhage (14.7%). In univariate analysis, recent digestive bleeding was associated with an increased risk of recurrence (OR 7.2, 95% CI 0.96 - 67.1). HBV (62.5%) is the main etiology of cirrhosis. The PNN rate at 250 - 499 mm3 (62.5%), the protein level 3 (75%). Patients on secondary prophylaxis with NORFLOXACIN were 25%. Recurrence of ISLA was treated with CEFTRIAXONE 2 g/24 hours. Conclusion: Recurrence of ISLA is serious, the predictive factors for recurrence are, hospital contact recent, the concept of iterative ascites punctures, the presence of HCC, the presence of hepatic encephalopathy and digestive bleeding.

关 键 词：Antibiotic CIRRHOSIS Risk factors Spontaneous Ascitic Fluid Infection RECURRENCE 

分 类 号：R73[医药卫生—肿瘤]