Charactistics of Anemia in Cirrhotics in the Gastroenterology Department at Brazzaville University Hospital  

作　　者：Clausina Mikolélé Ahoui Apendi Daulores Sylavnie Abena Ebembe Ngala Akoa Itoua-Ngaporo Jenny Carmela Angala Andzi Arnaud Mongo-Onkouo Jile Florient Mimiesse Monamou Rody Stéphane Ngami Mardochée Motoula Latou Marlyse Ngalessami Mouakosso Céline Sandra Adoua Deby Gassaye Blaise Irenée Atipo Ibara Clausina Mikolélé Ahoui Apendi;Daulores Sylavnie Abena Ebembe;Ngala Akoa Itoua-Ngaporo;Jenny Carmela Angala Andzi;Arnaud Mongo-Onkouo;Jile Florient Mimiesse Monamou;Rody Stéphane Ngami;Mardochée Motoula Latou;Marlyse Ngalessami Mouakosso;Céline Sandra Adoua;Deby Gassaye;Blaise Irenée Atipo Ibara(Department of Gastroenterology and Internal Medicine, Brazzaville University Hospital, Brazzaville, Republic of the Congo;Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Republic of the Congo)

机构地区：[1]Department of Gastroenterology and Internal Medicine, Brazzaville University Hospital, Brazzaville, Republic of the Congo [2]Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Republic of the Congo

出　　处：《Open Journal of Gastroenterology》2024年第11期402-413,共12页肠胃病学期刊（英文）

摘　　要：Objective: Study of the frequency of anemia, its characteristics and its relationship with different epidemiological, diagnostic and prognostic parameters of cirrhosis. Patients and methods: This was a retrospective descriptive study from January 2016 to December 2019 in the Gastroenterology and Internal Medicine department at the Brazzaville University Hospital. It concerned all cirrhotics hospitalized during the study period and presenting anemia. The epidemiological, diagnostic, and prognostic data studied were collected from medical records. The characteristics of anemia on the blood count were defined based on WHO values. The information collected was entered and processed with Excel 8.0 and EPI data 3.1 software. The Pearson chi2 test at the significance level ≤ 5% was used to compare the results. Results: We collected 102 files of cirrhotic patients during the study period. There were 63 men and 39 women, a sex ratio of 1.6. Among these patients, 77 presented anemia, i.e., a frequency of 75.5% with a male predominance (57.2%). Anemia increased without a significant relationship with age and was more severe in young female subjects (42.8%). The normochromic normocytic character was the most observed (52%). Anemia was more frequent in post-hepatitic cirrhosis, representing 67.5% of cases of anemia. It worsened during digestive bleeding, with the abundance of ascites and the severity of hepatic encephalopathy (p > 0.05). It was significantly associated with the drop in prothrombin level (63.6%), hypoalbuminemia (64.9%), and the Child-Pugh score (p < 0.05).Objective: Study of the frequency of anemia, its characteristics and its relationship with different epidemiological, diagnostic and prognostic parameters of cirrhosis. Patients and methods: This was a retrospective descriptive study from January 2016 to December 2019 in the Gastroenterology and Internal Medicine department at the Brazzaville University Hospital. It concerned all cirrhotics hospitalized during the study period and presenting anemia. The epidemiological, diagnostic, and prognostic data studied were collected from medical records. The characteristics of anemia on the blood count were defined based on WHO values. The information collected was entered and processed with Excel 8.0 and EPI data 3.1 software. The Pearson chi2 test at the significance level ≤ 5% was used to compare the results. Results: We collected 102 files of cirrhotic patients during the study period. There were 63 men and 39 women, a sex ratio of 1.6. Among these patients, 77 presented anemia, i.e., a frequency of 75.5% with a male predominance (57.2%). Anemia increased without a significant relationship with age and was more severe in young female subjects (42.8%). The normochromic normocytic character was the most observed (52%). Anemia was more frequent in post-hepatitic cirrhosis, representing 67.5% of cases of anemia. It worsened during digestive bleeding, with the abundance of ascites and the severity of hepatic encephalopathy (p > 0.05). It was significantly associated with the drop in prothrombin level (63.6%), hypoalbuminemia (64.9%), and the Child-Pugh score (p < 0.05).

关 键 词：ANEMIA CIRRHOSIS CHU BRAZZAVILLE 

分 类 号：R57[医药卫生—消化系统]