Ubiquitin-conjugating enzyme involved in the immune response caused by pathogens invasion  

作　　者：Liang Chen Chen Cheng Chunxia Zhang Qin Yao Ermi Zhao 

机构地区：[1]Institute of Life Sciences, Jiangsu University, Zhenjiang, China [2]Key Laboratory of Bio-Resources and Eco-Environment, College of Life Sciences, Sichuan University, Chengdu, China

出　　处：《Open Journal of Immunology》2013年第3期93-97,共5页免疫学期刊（英文）

摘　　要：Ubiquitin-proteasome pathway (UPP) is a significant way of protein degradation and modification in eukaryotic cell and involved in a complex series of intracellular processes. As a key component in UPP,?ubiquitin-conjugating enzyme (E2) plays an extremely important role in ubiquitin (Ub) transferring and substrate specific recognition. Abundant evidences have proved that UPP is involved in cells immune reaction caused by pathogens and the attendance of E2 has a significant effect on host cells and pathogen. This article presents an overview of the current research on E2s that is involved in immune response caused by viruses and bacteria.Ubiquitin-proteasome pathway (UPP) is a significant way of protein degradation and modification in eukaryotic cell and involved in a complex series of intracellular processes. As a key component in UPP,?ubiquitin-conjugating enzyme (E2) plays an extremely important role in ubiquitin (Ub) transferring and substrate specific recognition. Abundant evidences have proved that UPP is involved in cells immune reaction caused by pathogens and the attendance of E2 has a significant effect on host cells and pathogen. This article presents an overview of the current research on E2s that is involved in immune response caused by viruses and bacteria.

关 键 词：Ubiquitin-Conjugating Enzyme UBIQUITIN-PROTEASOME Pathway PATHOGEN Immune Response 

分 类 号：R73[医药卫生—肿瘤]