Monitoring Frequency of Haemoglobin, Calcium and Phosphorus and the Impact on Correction in Patients on Maintenance Haemodialysis in Douala-Cameroon  

作　　者：Halle Marie Patrice Kenfack Tatienou Orest Landry Tatang Mambap Alex Same Bebey Francine Fouda Hermine Ashuntantang Enow Gloria Halle Marie Patrice;Kenfack Tatienou Orest Landry;Tatang Mambap Alex;Same Bebey Francine;Fouda Hermine;Ashuntantang Enow Gloria(Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon;Department of Internal Medicine, Douala General Hospital, Douala, Cameroon;Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon;Bamenda Regional Hospital, Bamenda, Cameroon;Douala Laquintinie Hospital, Douala, Cameroon;Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon;Department of Internal Medicine, Yaounde General Hospital, Yaounde, Cameroon)

机构地区：[1]Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon [2]Department of Internal Medicine, Douala General Hospital, Douala, Cameroon [3]Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon [4]Bamenda Regional Hospital, Bamenda, Cameroon [5]Douala Laquintinie Hospital, Douala, Cameroon [6]Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon [7]Department of Internal Medicine, Yaounde General Hospital, Yaounde, Cameroon

出　　处：《Open Journal of Nephrology》2022年第3期311-322,共12页肾脏病（英文）

摘　　要：Background: There is scarcity of data on the actual frequency of routine blood work-up for patients on maintenance haemodialysis and how this affects the achievement of therapeutic goals in sub-Saharan Africa. This study aimed to review these in a referral hospital in Cameroon. Methods: A prospective hospital-based cohort study carried out from November 2019 to April 2020 including patients on maintenance haemodialysis in Douala general hospital. Patients were followed during 6 months to determine the frequency of monitoring of haemoglobin, serum calcium and phosphorus. Targeted values for haemoglobin were ≥10 g/dL, 80 - 100 mg/L for serum calcium and 25 - 45 mg/L for serum phosphorus. Pearson correlation test was used to define the correlation between monitoring frequencies and blood values at the end of the study. Results: For all 154 patients included in the study, the median frequency of monitoring for haemoglobin was once every 8 week (IQR: 6 - 12) and once every 12 weeks (IQR: 8 - 24) for serum calcium and phosphorus. The proportion of patients who achieved haemoglobin, serum calcium and phosphorus targets at the end of the study were 27.4%, 63% and 74% respectively. No correlation was found between the frequency of monitoring and the haemoglobin, serum phosphorus and calcium levels at the end of the study. Conclusion: The frequency of monitoring of serum haemoglobin, calcium and phosphorus by patients in this study was low with a high prevalence of patients not achieving target value.Background: There is scarcity of data on the actual frequency of routine blood work-up for patients on maintenance haemodialysis and how this affects the achievement of therapeutic goals in sub-Saharan Africa. This study aimed to review these in a referral hospital in Cameroon. Methods: A prospective hospital-based cohort study carried out from November 2019 to April 2020 including patients on maintenance haemodialysis in Douala general hospital. Patients were followed during 6 months to determine the frequency of monitoring of haemoglobin, serum calcium and phosphorus. Targeted values for haemoglobin were ≥10 g/dL, 80 - 100 mg/L for serum calcium and 25 - 45 mg/L for serum phosphorus. Pearson correlation test was used to define the correlation between monitoring frequencies and blood values at the end of the study. Results: For all 154 patients included in the study, the median frequency of monitoring for haemoglobin was once every 8 week (IQR: 6 - 12) and once every 12 weeks (IQR: 8 - 24) for serum calcium and phosphorus. The proportion of patients who achieved haemoglobin, serum calcium and phosphorus targets at the end of the study were 27.4%, 63% and 74% respectively. No correlation was found between the frequency of monitoring and the haemoglobin, serum phosphorus and calcium levels at the end of the study. Conclusion: The frequency of monitoring of serum haemoglobin, calcium and phosphorus by patients in this study was low with a high prevalence of patients not achieving target value.

关 键 词：MONITORING HAEMOGLOBIN PHOSPHORUS CALCIUM HAEMODIALYSIS Douala 

分 类 号：R73[医药卫生—肿瘤]