Alobar Holoprosencephaly in a Neonate: A Rare Case Report and Review of the Literature  

作　　者：Hanae Bahari Hanane Hajaj Anass Ayyad Sahar Messaoudi Rim Amrani Hanae Bahari;Hanane Hajaj;Anass Ayyad;Sahar Messaoudi;Rim Amrani(Department of Neonatology Intensive Care Unit, University Mohammed First, Oujda, Morocco;The Maternal-Child & Mental Health Research Laboratory, Oujda, Morocco)

机构地区：[1]Department of Neonatology Intensive Care Unit, University Mohammed First, Oujda, Morocco [2]The Maternal-Child & Mental Health Research Laboratory, Oujda, Morocco

出　　处：《Open Journal of Pediatrics》2023年第6期929-933,共5页儿科学期刊（英文）

摘　　要：Holoprosencephaly (HPE) is a rare brain malformation with multiple etiologies and is often associated with suggestive facial anomalies. This pathology is the result of a defect in the early development of the forebrain. There are three clinical forms: lobar, semi-lobar, alobar and another milder subtype of HPE called middle interhemispheric. In this clinical case, we present a newborn with alobar holoprosencephaly and we highlight the clinical, radiological and progressive clinical aspects of this illness during the neonatal period.Holoprosencephaly (HPE) is a rare brain malformation with multiple etiologies and is often associated with suggestive facial anomalies. This pathology is the result of a defect in the early development of the forebrain. There are three clinical forms: lobar, semi-lobar, alobar and another milder subtype of HPE called middle interhemispheric. In this clinical case, we present a newborn with alobar holoprosencephaly and we highlight the clinical, radiological and progressive clinical aspects of this illness during the neonatal period.

关 键 词：Polymalformative Syndrome HOLOPROSENCEPHALY HYDROCEPHALUS 

分 类 号：R73[医药卫生—肿瘤]