Juvenile Systemic Sclerosis: About 9 Cases  

作　　者：Kaoutar Danaoui Houda Nassih Khadija Oujennane Rabiy El Qadiry Aicha Bourrahouat Said Amal Imane Ait Sab Kaoutar Danaoui;Houda Nassih;Khadija Oujennane;Rabiy El Qadiry;Aicha Bourrahouat;Said Amal;Imane Ait Sab(B Pediatric Ward, Mohammed VI University Hospital Center, Marrakesh, Morocco;Dermatology Ward, Mohammed VI University Hospital Center, Marrakesh, Morocco)

机构地区：[1]B Pediatric Ward, Mohammed VI University Hospital Center, Marrakesh, Morocco [2]Dermatology Ward, Mohammed VI University Hospital Center, Marrakesh, Morocco

出　　处：《Open Journal of Pediatrics》2024年第2期320-326,共7页儿科学期刊（英文）

摘　　要：Scleroderma is a rare disease with two primary forms: localized scleroderma (LS) and systemic sclerosis (SSc). Both are chronic conditions that can manifest in various patterns (subtypes) and are linked to extracutaneous involvement in pediatric patients. Juvenile SSc poses a higher risk of morbidity and mortality, with patients facing life-threatening complications such as lung, heart, and visceral organ fibrosis, and vasculopathy. In contrast, mortality is extremely rare in juvenile LS, but patients are susceptible to significant morbidity, leading to severe disfigurement and functional impairment. Treatment for scleroderma aims to control inflammation and address specific issues. An early diagnosis significantly enhances the overall outcome. This study conducts a retrospective descriptive analysis aiming to document the clinical manifestations, management approaches, and outcomes of systemic sclerosis in a cohort of nine children receiving treatment for juvenile systemic sclerosis at Pediatric B department of Mohammed VI University, Hospital Center in Marrakech, Morocco.Scleroderma is a rare disease with two primary forms: localized scleroderma (LS) and systemic sclerosis (SSc). Both are chronic conditions that can manifest in various patterns (subtypes) and are linked to extracutaneous involvement in pediatric patients. Juvenile SSc poses a higher risk of morbidity and mortality, with patients facing life-threatening complications such as lung, heart, and visceral organ fibrosis, and vasculopathy. In contrast, mortality is extremely rare in juvenile LS, but patients are susceptible to significant morbidity, leading to severe disfigurement and functional impairment. Treatment for scleroderma aims to control inflammation and address specific issues. An early diagnosis significantly enhances the overall outcome. This study conducts a retrospective descriptive analysis aiming to document the clinical manifestations, management approaches, and outcomes of systemic sclerosis in a cohort of nine children receiving treatment for juvenile systemic sclerosis at Pediatric B department of Mohammed VI University, Hospital Center in Marrakech, Morocco.

关 键 词：SCLERODERMA Systemic Sclerosis CHILDREN PEDIATRIC 

分 类 号：R73[医药卫生—肿瘤]