Arterial and Venous Thrombosis following Vaccination against COVID-19 with Astra-Zeneca Vaccine Revealing Thrombophilia  

作　　者：Bah Mamadou Bassirou Doumbouya Amadou Dioulde Balde Mamadou Aliou Balde Thierno Hamidou Sylla Ibrahima Sory Balde Elhadj Yaya Kone Alpha Barry Ibrahima Sory Samoura Sana Beavogui Mariam Diakité Souleymane Balde Mamadou Dadhi Bah Mamadou Bassirou;Doumbouya Amadou Dioulde;Balde Mamadou Aliou;Balde Thierno Hamidou;Sylla Ibrahima Sory;Balde Elhadj Yaya;Kone Alpha;Barry Ibrahima Sory;Samoura Sana;Beavogui Mariam;Diakité Souleymane;Balde Mamadou Dadhi(Cardiology Department, Ignace Deen Hospital, Conakry, Guinea;Imaging Department, Ignace Deen Hospital, Conakry, Guinea)

机构地区：[1]Cardiology Department, Ignace Deen Hospital, Conakry, Guinea [2]Imaging Department, Ignace Deen Hospital, Conakry, Guinea

出　　处：《World Journal of Cardiovascular Diseases》2023年第4期198-204,共7页心血管病（英文）

摘　　要：Vaccination against COVID-19 is the most recognised means of containing the pandemic. Vaccines are not without side effects, particularly vascular thrombosis. But before blaming the vaccines, a thorough assessment of thrombotic risk factors is necessary. We report a case of arterial and venous thrombosis after vaccination with AstraZeneca revealing an exaggeration of factor VIII in a 37-year-old female patient. The angioscanner showed a venous thrombosis of the right subclavian, a pulmonary embolism and the presence of a thrombus in the aorta. The biology was in favour of a high level of factor VIII. The patient was treated with an antivitamin K, and the clinical evolution was favourable.Vaccination against COVID-19 is the most recognised means of containing the pandemic. Vaccines are not without side effects, particularly vascular thrombosis. But before blaming the vaccines, a thorough assessment of thrombotic risk factors is necessary. We report a case of arterial and venous thrombosis after vaccination with AstraZeneca revealing an exaggeration of factor VIII in a 37-year-old female patient. The angioscanner showed a venous thrombosis of the right subclavian, a pulmonary embolism and the presence of a thrombus in the aorta. The biology was in favour of a high level of factor VIII. The patient was treated with an antivitamin K, and the clinical evolution was favourable.

关 键 词：THROMBOPHILIA THROMBOSIS VACCINE ASTRAZENECA 

分 类 号：R73[医药卫生—肿瘤]