DNA Sequencing: Current State and Prospects of Development  

作　　者：Lusine Gasparyan Ilya Mazo Vahan Simonyan Ferdinand Gasparyan 

机构地区：[1]Argentys Informatics, LLC, Gaithersburg MD, USA [2]Yerevan State University, Yerevan, Armenia [3]The Department of Biochemistry & Molecular Medicine, The School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA

出　　处：《Open Journal of Biophysics》2019年第3期169-197,共29页生物物理学期刊（英文）

摘　　要：In this review, we collected and classified the stages of development of DNA sequencing methods and described its peculiarities. We pay attention mostly on solid-stead nanopore sequencing methods. Detailed discussion of the peculiarity and feasibility of the electrical methods of DNA sequencing is discussed. The detail analyses of the literature data, some critical considerations and the potential ways of optimization of DNA nanopore sequencing were presented.In this review, we collected and classified the stages of development of DNA sequencing methods and described its peculiarities. We pay attention mostly on solid-stead nanopore sequencing methods. Detailed discussion of the peculiarity and feasibility of the electrical methods of DNA sequencing is discussed. The detail analyses of the literature data, some critical considerations and the potential ways of optimization of DNA nanopore sequencing were presented.

关 键 词：DNA Sequencing ISFET SENSOR EIS SENSOR Solid-Stead NANOPORE 

分 类 号：R73[医药卫生—肿瘤]