Comparison of Serum Phospholipase A₂Activities of All Known Extant Crocodylian Species  

作　　者：Mark Merchant Charles McAdon Stephanie Mead Justin McFatter Caleb D. McMahan Rebeckah Griffith Christopher M. Murray 

机构地区：[1]Department of Chemistry, McNeese State University, Lake Charles, LA, USA [2]The Field Museum of Natural History, Chicago, IL, USA [3]Department of Math, Computer Science, and Statistics, McNeese State University, Lake Charles, LA, USA [4]Department of Biology, Tennessee Technological University, Cookeville, TN, USA

出　　处：《Advances in Biological Chemistry》2017年第4期151-160,共10页生物化学进展（英文）

摘　　要：Serum samples from all 23 extant crocodilian species were tested for phospholipase A2 (PLA2) activity against nine different bacterial species. The data were used?to generate a PLA2 activity profile for each crocodilian species, and the data were used to compare the activities of the three main lineages (Alligatoridae,?Crocodylidae, and Gavialidae), the seven different genera, and to compare all?of the 23 individual species. The data revealed that the three lineages ofcrocodilians (Alligatoridae, Crocodylidae, and Gavialidae) exhibited PLA2 activities toward nine species of bacteria that were statistically?distinguishable. In?addition,?the PLA2 activities of crocodilians in a specific genus tended to be more similar to other?members in their genus than to members of other crocodilian genera.Serum samples from all 23 extant crocodilian species were tested for phospholipase A2 (PLA2) activity against nine different bacterial species. The data were used?to generate a PLA2 activity profile for each crocodilian species, and the data were used to compare the activities of the three main lineages (Alligatoridae,?Crocodylidae, and Gavialidae), the seven different genera, and to compare all?of the 23 individual species. The data revealed that the three lineages ofcrocodilians (Alligatoridae, Crocodylidae, and Gavialidae) exhibited PLA2 activities toward nine species of bacteria that were statistically?distinguishable. In?addition,?the PLA2 activities of crocodilians in a specific genus tended to be more similar to other?members in their genus than to members of other crocodilian genera.

关 键 词：Antibacterial Antimicrobial CROCODILIAN CROCODYLIA Crocodylidae Gavialidae INNATE Immunity Phylogeny PLA2 

分 类 号：R73[医药卫生—肿瘤]