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INNATE: 作品数：288被引量：1208H指数：16; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：田志刚孙汭侯昕沈际佳宋静更多>>; 相关机构：中国科学技术大学安徽医科大学中南大学中国科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>

Systematic analysis of innate immune-related genes in the silkworm:Application to antiviral research: 《Insect Science》2025年第1期151-171,共21页Junming Xia Ruoxuan Peng Shigang Fei Mian Muhammad Awais Wenxuan Lai Yigui Huang Hailin Wu Yue Yu Lingying Liang Luc Swevers Jingchen Sun Min Feng; supported by the National Natural Science Foundation of China(32372945);Guangzhou Science and Technology Plan(202201010369);Natural Science Foundation of Guangdong Basic and Applied Basic Research Fund(2022A1515012657);South China Agricultural University high-level talent launch project.; The silkworm,a crucial model organism of the Lepidoptera,offers an excellent platform for investigating the molecular mechanisms underlying the innate immune response of insects toward pathogens.Over the years,researc...; 关键词：antiviral defense BMNPV Bombyx mori innate immunity SilkDB 3.0

Unveiling the dynamic role of innate and adaptive immune cells in COPD pathogenesis induced by cigarette smoke: 《Life Research》2024年第4期29-41,共13页Dur E Maknoon Razia Syed Sib Tul Hassan Shah Tabish Faheem; Chronic obstructive pulmonary disease(COPD)is a multifaceted syndrome characterized by a dysregulated inflammatory cascade within the respiratory system,primarily triggered by exposure to harmful particles and gases,n...; 关键词：chronic obstructive pulmonary disease innate immunity adaptive immunity cigarette smoke inflammation oxidative stress protease-antiprotease imbalance

GABAergic Retinal Ganglion Cells Projecting to the Superior Colliculus Mediate the Looming-Evoked Flight Response: 《Neuroscience Bulletin》2024年第12期1886-1900,共15页Man Yuan Gao Tan Danrui Cai Xue Luo Kejiong Shen Qinqin Deng Xinlan Lei Wen-Bo Zeng Min-Hua Luo Lu Huang Chaoran Ren Yin Shen; supported by grants from the National Key R&D Program of China(2017YFE0103400);the National Natural Science Foundation of China(81470628 and 82471086).; The looming stimulus-evoked flight response to approaching predators is a defensive behavior in most animals. However, how looming stimuli are detected in the retina and transmitted to the brain remains unclear. Here,...; 关键词：scpgRGCs Innate defensive behavior GABA LOOMING Superior colliculus Flight response

Current progress of virus-mediated gene therapy-where we are and what we need: 《感染控制(英文)》2024年第3期8-20,共13页Wei Miao; Viral vectors are instrumental in gene therapy and vaccination,addressing a spectrum of diseases from genetic disorders to cancer.Despite their promise,their clinical utility is hampered by the propensity to provoke h...; 关键词：viral vectors IMMUNOGENICITY gene therapy innate and adaptive immune systems immune evasion strategies

Phosphorylation of CAX transporters controls Ca^(2+) homeostasi: 《Plant Communications》2024年第9期8-11,共4页Jinggeng Zhou Yunxia He Xiangzong Meng; supported by the National Natural Science Foundation of China(grants 32370291 to J.Z.and 32370313 to X.M.);the Natural Science Foundation of Shanghai(grant 22ZR1446300 to J.Z.).; Plants rely on a sophisticated innate immune system to recognize and defend against invading pathogens.The first line of plant innate immunity,called pattern-triggered immunity(PTI),is initiated upon detection of path...; 关键词：IMMUNITY pattern INNATE

Innate and adaptive immune responses that control lymph-borne viruses in the draining lymph node被引量：1: 《Cellular & Molecular Immunology》2024年第9期999-1007,共9页Carolina R.Melo-Silva Luis J.Sigal; The interstitial fluids in tissues are constantly drained into the lymph nodes(LNs)as lymph through afferent lymphatic vessels and from LNs into the blood through efferent lymphatics.LNs are strategically positioned a...; 关键词：Virus infection lymph borne virus lymph node virus control innate immunity adaptive immunity dendritic cells Langerhans cells macrophages inflammatory monocytes natural killer cells CD8+T-cells

Tissue-specific features of innate lymphoid cells in antiviral defense被引量：2: 《Cellular & Molecular Immunology》2024年第9期1036-1050,共15页Sytse J.Piersma; Innate lymphocytes(ILCs)rapidly respond to and protect against invading pathogens and cancer.ILCs include natural killer(NK)cells,ILC1s,ILC2s,ILC3s,and lymphoid tissue inducer(LTi)cells and include type I,type II,and ...; 关键词：NK cell innate lymphoid cell tissue microenvironment virus infection anti-viral immunity

Pharmacological Investigation on the Qi-Invigorating Action of Schisandrin B: Effects on Mitochondrial ATP Generation in Multiple Tissues and Innate/Adaptive Immunity in Mice: 《Chinese Medicine》2024年第2期15-26,共12页Hoi Yan Leung Suen Chit Sze Kam Ming Ko; Schisandrae Fructus, containing schisandrin B (Sch B) as its main active component, is recognized in traditional Chinese medicine (TCM) for its Qi-invigorating properties in the five visceral organs. Our laboratory ha...; 关键词：Zheng Qi Schisandrin B MITOCHONDRIA ATP Generation Glutathione Redox Innate Immunity Adaptive Immunity Natural Killer Cell Activity Splenocyte Proliferation

The chemerin-CMKLR1 axis in keratinocytes impairs innate host defense against cutaneous Staphylococcus aureus infection被引量：2: 《Cellular & Molecular Immunology》2024年第6期533-545,共13页Yu Chen Yan Song Zhe Wang Yangfan Lai Wei Yin Qian Cai Miaomiao Han Yiheng Cai Yushan Xue Zhengrong Chen Xi Li Jing Chen Min Li Huabin Li Rui He; Shanghai Science and Technology Commission 23ZR1461500(to RH);Key Laboratory of Medical Molecular Virology(MOE/NHC)FDMVK-2021001(to RH);The National Natural Science Foundation of China Grant 82271138(to HL);National Key Research and Development Program of China 2020YFC2005003(to JC).; The skin is the most common site of Staphylococcus aureus infection,which can lead to various diseases,including invasive and life-threatening infections,through evasion of host defense.However,little is known about t...; 关键词：Chemerin-CMKLR1 Staphylococcus aureus NEUTROPHIL IL-33 KERATINOCYTES

Use of an immunocapture device to detect cytokine release in discrete brain regions: 《Neural Regeneration Research》2024年第4期703-704,共2页Matthew G.Frank Michael V.Baratta; supported by an American Australian Association Fellowship(to MVB).; Production of proinflammatory cytokines in the central nervous system is a key process in the neuroinflammatory response to trauma,infection,and neurodegenerative diseases(Kumar,2019).These intercellular signaling mol...; 关键词：SYSTEM RELEASE INNATE

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