Synthesis of Novel Bis-enaminones by KHSO4-assisted Facile Michael Addition-elimination Reaction of 3-(dimethylamino)-1-phenylprop-2-en-1-ones with Diamines in Water  

作　　者：Asem Satyapati Devi Philippe Helissey Jai Narain Vishwakarma 

机构地区：[1]不详

出　　处：《Green and Sustainable Chemistry》2011年第2期31-34,共4页绿色与可持续化学（英文）

摘　　要：3-(Dimethylamino)-1-phenylprop-2-en-1-ones (formylated acetophenones) 1 reacted with aliphatic diamines in water assisted by KHSO4 to give bis-enaminones 2a-h in good yields. Compound 1 also reacted with o-phenylenediamine under similar conditions to produce bis-enaminones 3 instead of benzodiazepines 4 in excellent yields.3-(Dimethylamino)-1-phenylprop-2-en-1-ones (formylated acetophenones) 1 reacted with aliphatic diamines in water assisted by KHSO4 to give bis-enaminones 2a-h in good yields. Compound 1 also reacted with o-phenylenediamine under similar conditions to produce bis-enaminones 3 instead of benzodiazepines 4 in excellent yields.

关 键 词：ENAMINONE Bis-enaminone Formylated Acetophenone Michael ADDITION-ELIMINATION FORMYLATION Dimethylformamide-dimethylacetal 

分 类 号：O6[理学—化学]