Enantioselective Aldol Reactions and Michael Additions Using Proline Derivatives as Organocatalysts  

作　　者：Mathieu Wagner Yohan Contie Clotilde Ferroud Gilbert Revial 

机构地区：[1]Conservatoire National des Arts et Métiers, Laboratoire de Transformations Chimiques et Pharmaceutiques, Paris, France

出　　处：《International Journal of Organic Chemistry》2014年第1期55-67,共13页有机化学国际期刊（英文）

摘　　要：Six compounds including five proline derivatives have been prepared and tested as chiral organocatalysts for enantioselective aldol reactions and Michael additions. The enantiomeric excesses, which are highly dependent on the molecular structure of catalysts as well as experimental conditions, have reached over 98%.Six compounds including five proline derivatives have been prepared and tested as chiral organocatalysts for enantioselective aldol reactions and Michael additions. The enantiomeric excesses, which are highly dependent on the molecular structure of catalysts as well as experimental conditions, have reached over 98%.

关 键 词：ALDOL Reactions MICHAEL ADDITIONS ENANTIOSELECTIVE ORGANOCATALYSTS PROLINE Derivatives 

分 类 号：O6[理学—化学]