This work was supported by grants from the key grant of the National Natural Science Foundation(no.30630060,Y Zhao);the Knowledge Innovation Program of Chinese Academy of Sciences(no.KSCX2-SW-333,Y Zhao);the National Natural Science Foundation for Distinguished Young Scholars(no.C03020504,Y Zhao).
The diversity of alloreactive T cells in graft rejection and the presence of extensive crossreactivity among alloreactive T cells indicate thatthe induction oftransplantation tolerancemay fundamentally alter the size ...
grants from the National Natural Science Foundation for Distinguished Young Scholars (C03020504, Y.Z.);Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-SW-333, Y.Z.);the Scientific Research Foundation for the Returned Overseas Chinese Scholars of State Education Ministry (2005-546, Y.Z.)
Xenogeneic thymus transplantation can efficiently induce specific immune tolerance to donor antigens in athymic recipients. However, many nude mice suffer from autoimmune diseases (AID) for over 10 weeks after xenog...
This work was supported by grants from the National Natural Science Foundation for Distinguished Young Scholars(C03020504,Y.Z.);the National Basic Research Program(973 Program,2003CB515501,Y.Z.);100 Quality Vocational Colleges of Chinese Academy of Sciences(2003-85,Y.Z.);the Knowledge Innovation Program of Chinese Academy of Sciences(KSCX2-SW-333,Y.Z.);the Scientific Research Foundation for the Returned 0verseas Chinese Scholars of State Education Ministry(2005-546,Y.Z.).
The homeostasis of the immune system depends on the balance between the immune response to an invaded pathogen and the immune tolerance to self antigens. Both central and peripheral tolerances are important mechanisms...