国家自然科学基金(60671018)

作品数:4被引量:8H指数:2
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相关作者:孙啸卢志远王亚旭胡敏菁逯雯雯更多>>
相关机构:东南大学更多>>
相关期刊:《Science Bulletin》《Journal of Southeast University(English Edition)》《生物信息学》更多>>
相关主题:RNA基因MICRORNAFISHER精确检验COMMON上皮细胞更多>>
相关领域:生物学轻工技术与工程化学工程更多>>
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Identification of common microRNA-mRNA regulatory biomodules in human epithelial cancer被引量:3
《Chinese Science Bulletin》2010年第31期3576-3589,共14页YANG XiNan LEE Younghee FAN Hong SUN Xiao LUSSIER Yves A 
supported by the National Natural Science Foundation of China (60971099,60671018 and 60771024);Center for Multilevel Analyses of Genomic and Cellular Networks (1U54CA121852-01A1);the Cancer Research Foundation
The complex regulatory network between microRNAs and gene expression remains an unclear domain of active research.We proposed to address in part this complex regulation with a novel approach for the genome-wide identi...
关键词:RNA基因 上皮细胞 监管机制 FISHER精确检验 癌症 MICRORNA 人类 识别 
Analysis of nucleosome positioning in promoters of miRNA genes and protein-coding genes被引量:1
《Chinese Science Bulletin》2010年第22期2347-2352,共6页LIU HongDe ZHANG DeJin XIE JianMing YUAN ZhiDong MA Xin LU ZhiYuan GONG LeJun SUN Xiao 
supported by the National Natural Science Foundation of China (60671018 and 30800209)
Nucleosome positioning in promoters is important for gene transcription regulation. In this paper, with a nucleosome prediction model, curvature profile, the characteristics of nucleosome positioning in promoters are ...
关键词:蛋白编码基因 基因启动子 核小体 点定位 RNA基因 miRNA 蛋白质编码 转录起始位点 
面向新一代基因组测序技术的序列拼接算法被引量:2
《生物信息学》2010年第3期248-253,共6页逯雯雯 卢志远 王亚旭 孙啸 
国家自然科学基金(60671018)
随着新一代测序技术的发展,新的拼接算法应运而生。介绍了目前国际上广泛认可的几种新的拼接算法的基本原理与具体步骤,分析每种算法的优缺点以及适用范围。用Helicobacter acinonychis的Illumina 1G测序数据检测SSAKE,VCAKE,SHARCGS以...
关键词:基因组测序 序列拼接 短片段 
Support vector machine for prediction of siRNA silencing efficacy被引量:2
《Journal of Southeast University(English Edition)》2006年第4期501-504,共4页吴建盛 胡敏菁 周童 翁建洪 江澎 孙啸 
The National Natural Science Foundation of China(No60671018,60121101)
In order to assist the design of short interfering ribonucleic acids (siRNA), 573 non-redundant siRNAs were collected from published literatures and the relationship between siRNAs sequences and RNA interference (R...
关键词:short interfering ribonucleic acid (siRNA) support vector machine base-base correlation receive operating characteristic (ROC) curve 
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