国家重点基础研究发展计划(2009CB825504)

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相关期刊：《Protein & Cell》更多>>
相关主题：CRYSTAL_STRUCTURESCATALYTICBIVARGEINTEGRASE更多>>
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Crystal structures of catalytic core domain of BIV integrase: implications for the interaction between integrase and target DNA
《Protein & Cell》2010年第4期363-370,共8页Xue Yao Shasha Fang Wentao Qiao Yunqi Geng Yuequan Shen 
This study was supported by grants from the Ministry of Science and Technology of China(Grant Nos.2007CB914301,2009CB825504,2006AA02A319,2006AA020502);the Ministry of Health of China(Grant No.2008ZX10001-002);the National Natural Science Foundation of China(Grant Nos.30770428,30940015);the TBR programs(Grant Nos.08QTPTJC28200,08SYSYTC00200,07JCYBJC19200).
Integrase plays a critical role in the recombination of viral DNA into the host genome.Therefore,over the past decade,it has been a hot target of drug design in the fight against type 1 human immunodeficiency virus(HI...
关键词：bovine immunodeficiency virus INTEGRASE catalytic core domain crystal structure DIMERIZATION 
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