国家高技术研究发展计划(2004AA2Z3785)

作品数:1被引量:6H指数:1
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相关期刊:《Acta Pharmacologica Sinica》更多>>
相关主题:MDA-MB-435MATRIX_METALLOPROTEINASESCCR7TOPOTECANCHEMOKINE更多>>
相关领域:医药卫生更多>>
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Topotecan inhibits cancer cell migration by down-regulation of chemokine CC motif receptor 7 and matrix metalloproteinases被引量:6
《Acta Pharmacologica Sinica》2009年第5期628-636,共9页Sen-sen LIN Li SUN Yan-kai ZHANG Ren-ping ZHAO Wen-lu LIANG Sheng-tao YUAN Lu-yong ZHANG 
Acknowledgements This project was financially supported by the National High Technology Research and Development Program of China (863 Program, No 2004AA2Z3785) and by a grant from the Natural Science Foundation of Jiangsu province (No BK2006150).
Aim: The aim of this study was to investigate the effect of topotecan (TPT) on cancer cell migration. Methods: Growth inhibition of TPT was analyzed by MTT assay, and cancer cell migration was measured by transwel...
关键词:TOPOTECAN MDA-MB-435 MDA-MB-231 cancer metastasis CXCR4 CCR7 MMP-2 MMP-9 
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