云南高校图书馆联盟文献共享服务平台- TOPOTECAN

TOPOTECAN: 作品数：32被引量：65H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：潘启超徐梅朱孝荣袁红花吴强更多>>; 相关机构：北京协和医院中山医科大学徐州医科大学江苏省肿瘤医院更多>>; 相关期刊：《Journal of Cancer Metastasis and Treatment》《CellBio》《广州医药》《现代肿瘤医学》更多>>; 相关基金：国家自然科学基金江苏省科技厅社会发展基金广东省自然科学基金国家高技术研究发展计划更多>>

Changes of protein expression during tumorosphere formation of small cell lung cancer circulating tumor cells: 《Oncology Research》2023年第1期13-22,共10页SANDRA STICKLER BARBARA RATH MAXIMILIAN HOCHMAIR CLEMENS LANG LUKAS WEIGL GERHARD HAMILTON; partially funded by the“Medical Scientific Fund of the Mayor of the City of Vienna”,Grant Number 21040 to Dr.C.Lang.; Small cell lung cancer(SCLC)is frequently disseminated and has a dismal prognosis with survival times of approximately two years.This cancer responds well to initial chemotherapy but recurs within a short time as a gl...; 关键词：SCLC SPHEROID CHEMORESISTANCE EPCAM TOPOTECAN EPIRUBICIN

FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11被引量：1: 《Acta Pharmacologica Sinica》2022年第8期2119-2127,共9页Yan-ping Yin Li-ying Ma Guo-zhen Cao Jing-han Hua Xiao-tong Lv Wen-chu Lin; supported by National Natural Science Foundation of China(81972191 and 81672647);Science and Technology Major Project of Anhui Province(18030801140);the 100-Talent Program of Chinese Academy of Sciences.; The response rate of topotecan,as a second-line chemotherapeutic drug for small cell lung cancer,is~20%.DNA/RNA helicase SLFN11(schlafen family member 11),a member of the Schlafen(SLFN)family,is a crucial determinant ...; 关键词：small cell lung cancer TOPOTECAN DNA damage response FK228 SLFN11 METHYLATION epigenetic modulation

Protection of small-cell lung cancer circulating tumor cells by cellular fragmentation被引量：1: 《Journal of Cancer Metastasis and Treatment》2020年第1期345-354,共10页Barbara Rath Adelina Plangger Doris Moser Maximilian Hochmair Ernst Ulsperger Gerhard Hamilton; Aim:Small-cell lung cancer(SCLC)disseminates aggressively and may exhibit high chemoresistance and poor survival rates.In this study,we aimed to investigate a new mechanism of drug resistance for SCLC circulating tumo...; 关键词：Small cell lung cancer circulating tumor cells SHEDDING TOPOTECAN

A Preliminary Study on Combination Therapy of Artemisinin Dimer Oxime and Topotecan against Nonsmall Cell Lung Cancer in Mice被引量：3: 《World Journal of Traditional Chinese Medicine》2018年第1期8-14,共7页Mohammad K.Ashfaq Mohamed Sadek Abdel-Bakky Mir Tahir Maqbool Waseem Gul Mahmoud A.ElSohly; Background: Artemisinin dimer oxime – dimer molecule synthesized from artemisinin possesses high bioavailability and marked in vitro anticancer activities against solid tumor?derived cell lines, endothelial cell prol...; 关键词：ARTEMISININ cancer dimer oxime TOPOTECAN XENOGRAFTS

Therapeutic Efficacy of Genistein-Topotecan Combination Compared to Vitamin D3-Topotecan Combination in LNCaP Prostate Cancer Cells: 《CellBio》2013年第3期97-104,共8页Shreyasee Chakraborty Bibiana Sandoval-Bernal James Kumi-Diaka; Background: Prostate cancer is the most common cancer in men over the age of 60 in Western countries. An estimated 241,740 new cases of prostate cancer have been diagnosed in the United States in 2012 with a death tol...; 关键词：TOPOTECAN GENISTEIN VITAMIN D PROSTATE Cancer

Synergistic Anticancer Activity of Topotecan— Cyclin-Dependent Kinase Inhibitor Combinations against Drug-Resistant Small Cell Lung Cancer (SCLC) Cell Lines被引量：1: 《Journal of Cancer Therapy》2013年第8期47-53,共7页Gerhard Hamilton Ulrike Olszewski, Lukas Klameth Ernst Ulsperger Klaus Geissler; Extended-stage small cell lung cancer (SCLC) responds to platinum/vepeside-based first-line chemotherapy but relapses rapidly as drug-resistant tumor. Topotecan (TPT) is the single chemotherapeutic agent approved for ...; 关键词：Small Cell Lung Cancer CHEMORESISTANCE TOPOTECAN CDK Inhibitor OLOMOUCINE ROSCOVITINE

Topotecan Use for Second-Line Treatment in Patients with Recurrent or Metastatic Cervical Cancer at Brazilian National Cancer Institute (INCA): 《Journal of Cancer Therapy》2013年第6期1095-1099,共5页Leandro Nascimento de Oliveira Flávia Vieira Guerra Alves Paulo Alexandre Ribeiro Mora Claudio Calazan do Carmo Angélica Nogueira-Rodrigues Alvaro Henrique Ingles Garces Andréia Cristina de Melo; Objective: Cervical cancer represents the third most commonly diagnosed cancer and is an important cause of death for women suffering with malignancies. Patients who are refractory or progressed after first-line palli...; 关键词：TOPOTECAN CERVICAL Cancer PALLIATIVE Treatment

Beyond retinocytomas： clinical benefit of topotecan in the management of other intra-cranial tumors especially glioblastomas: 《Chinese Medical Journal》2013年第9期1635-1635,共1页; To the editor： Zhang et al1 have provided interesting data in their recent article. Topotecan may of clinical benefit in themanagement of other intra-cranial tumors especially glioblastomas.

Effect of topotecan on retinocytoma cell apoptosis and expression of Livin and PTEN被引量：12: 《Chinese Medical Journal》2013年第2期340-344,共5页ZHANG Meng SHAN Bao-en YUAN Nai-fen LIU Wei; Background Retinocytoma （RB） is a very common intraocular malignant tumor during infancy. Chemotherapy has gradually been used as the first-line treatment for intraocular RB in recent years. In this study, Livin and...; 关键词：retinocytoma LIVIN PTEN immunohistochemistry flow cytometry Western blotting

A Phase Ⅰ trial of dose escalation of topotecan combined with whole brain radiotherapy for brain metastasis in lung cancer被引量：1: 《The Chinese-German Journal of Clinical Oncology》2012年第8期449-451,共3页Xiaohui Ge Wenyan Zhao Xiaocang Ren Yongqiang Wang Zhigang Li Yanqi Li Yuee Liu Qiang Lin; Objective The aim of this study was to define the maximum-tolerated dose (MTD) and observe the toxicity of escalating topotecan combined whole brain radiotherapy for brain metastasis in lung cancer.; 关键词：brain metastasis neoplasm/lung cancer TOPOTECAN RADIOTHERAPY CHEMOTHERAPY maximum tolerated dose

TOPOTECAN