supported by Fundacja ORLEN(donation No.161/XI/2022)(to GW).
Neurodegenerative diseases are defined as disorders resulting from the slow and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous tissue.They can lead to...
Genistein phospholipid complex(GS-PC)was produced in order to increase the solubility and antioxidant activity of genistein(GS),an insoluble natural polyphenol compound.By using the solvent evaporation process,GS-PC w...
supported by the Natural Science Foundation of Heilongjiang Province[LH2021H011].
Lipid metabolism refers to the biochemical processes involved in synthesising,storing,utilising,and breaking down lipids in living organisms.Lipids are essential for various physiological functions,including energy st...
The authors thank the Sadowski laboratory for sharing pIOX179.This project received funding from the European Union’s Horizon 2020 re-search and innovation program under grant agreement no.814650.
Genistein,an isoflavone found mainly in legumes,has been shown to have numerous health benefits for hu-mans.Therefore,there is substantial interest in producing it using microbial cell factories.To aid in screening fo...
the National Natural Science Foundation of China(Grant No.22278443);CAMS Innovation Fund for Medical Sciences(Grant No.2022-I2M-1-015);the Chinese Pharmacopoeia Commission Drug Standard Promoting Fund(Grant No.2023Y11)for financial support.
With various potential health-promoting bioactivities,genistein has great prospects in treatment of a series of complex diseases and metabolic syndromes such as cancer,diabetes,cardiovascular diseases,menopausal sympt...
supported by the Multi-Year Research Grants from the University of Macao(No.MYRG2019–00032-ICMS);Natural Science Foundation of Jiangsu Province(No.BK20210912);the startup grant of Xuzhou Medical University(D2021004);Macao Science and Technology Development Fund(No.0017/2019/AKP)。
Pulmonary delivery is an effective drug delivery strategy for the treatment of local respiratory diseases.However,the rapid systemic absorption through the lung due to the thin barrier and persistent lung clearances i...
Supported by a grant from the Scientific Research Project of Shanxi Provincial Health Commission(No.2021166)。
Objective To investigate the anticancer effect of a novel derivative of genistein(5-hydroxy-4’-nitro-7-propionyloxy-genistein,HNPG)on human ovarian cancer HO-8910 cells and its possible molecular mechanism.Methods HO...
Supported by National Key Research and Development Program of China(2018YFC1706101);Science and Technology Program of Sichuan Province(Key Research and Development Project)(2021YFS0043);Standard Improvement of Traditional Chinese Medicine(Ethnic Medicine)of Sichuan Provincial Drug Administration(510201202102305);2022 Leading Talents Support Program of National Ethnic Affairs Commission;University-level Innovation Team Special Project of Basic Research Funds for Central Universities and Colleges(ZYN2022067)。
[Objectives]The paper was to establish the quality standard of Yi herb medicine Millettia dielsiana.[Methods]Yi herb medicine M.dielsiana was qualitatively identified by microscopic identification and thin layer ident...
Exposure to Bisphenol A (BPA) worldwide is on the increase. Its toxicities in various tissues expressing estrogen receptors have been reported. However, limited information exists on its effects on the gastric tissue....