ISOFLAVONE

作品数：77被引量：243H指数：8
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Flavonoid from the twigs and leaves of Erythrina variegata
《Journal of Chinese Pharmaceutical Sciences》2024年第7期659-665,共7页Yongchun Gao Xi Yang Liqin Wang 
National Natural Science Foundation of China(Grant No.32060099).
In the present study,17 flavonoids,including 9 prenylated isoflavones,4 isoflavones,3 flavanones and 1 flavone,were isolated from the twigs and leaves of Erythrina variegata.By NMR spectroscopic means and comparision ...
关键词：Erythrina variegata ERYTHRINA Prenylated isoflavone ISOFLAVONE 
Effect of red clover isoflavones on hormone,immune,inflammatory,and plasma biochemistry in lactating dairy cows
《Animal Nutrition》2024年第1期306-312,共7页Shiqi Zhang Xiaoyin Zhang Zhanbo Xiong Kexin Li Yuan Gao Ying Bu Nan Zheng Shengguo Zhao Jiaqi Wang 
supported by the National Key R&D Program of China(2022YFD1301000);the Modern Agro-Industry Technology Research System of China(CARS-36);the State Key Laboratory of Animal Nutrition(2004DA125184G2108);Key Program of Inner Mongolia(2021-NDTIC-2)
This study was to conducted to investigate the effect of red clover isoflavones on the health indicated by immune status and blood biochemistry in dairy cows.Sixty-eight healthy Holstein lactating cows were randomly d...
关键词：Dairy cow Red clover isoflavone Immunity ANTI-INFLAMMATORY 
Pueraria isoflavones inhibit XOD and GLUT9 to decrease uric acid production and promote uric acid excretion, respectively
《Journal of Hainan Medical University》2024年第2期13-13,共1页LI Tong LIANG Bao-yue LIU Han FANG Shao-ting ZHANG Ming-jie LUO Jing CHEN Pin-nuo SONG Ji-chi CHU Xiao HUANG Chun-xia 
National Innovation and Entrepreneurship Training Program for College Students(No.S202010823014);Hunan Provincial College Student Innovation Training Project,No.(2021)199(S202110823045)。
Objective: To analyze the possible mechanism of Pueraria isoflavones inhibiting XOD and GLUT9 to reduce uric acid production and promote uric acid excretion. Methods: August 2021-April 2022, a total of forty SPF male ...
关键词：Kudzu root ISOFLAVONE HYPERURICEMIA Xanthine oxidase Human glucose transporter 9 Inflammation Reduce generation Promote excretion 
A highly selective cell-based fluorescent biosensor for genistein detection被引量：2
《Engineering Microbiology》2023年第2期72-82,共11页Lucy Fang-I Chao Dany Liu Verena Siewers 
The authors thank the Sadowski laboratory for sharing pIOX179.This project received funding from the European Union’s Horizon 2020 re-search and innovation program under grant agreement no.814650.
Genistein,an isoflavone found mainly in legumes,has been shown to have numerous health benefits for hu-mans.Therefore,there is substantial interest in producing it using microbial cell factories.To aid in screening fo...
关键词：BIOSENSOR GENISTEIN Flavonoid ISOFLAVONE 
New dual functional CYP450 gene involves in isoflavone biosynthesis in Glycine max L.
《Synthetic and Systems Biotechnology》2023年第1期157-167,共11页Yaying Xia Chunfeng He Su Yan Jinyue Liu Haijun Huang Xue Li Qian Su Wenbo Jiang Yongzhen Pang 
supported by the Agricultural Science and Technology Innovation Program (ASTIP-IAS10).
Glycine max L.accumulates a large amount of isoflavonoid compounds,which is beneficial for plant defense,plant-microbe symbiotic interactions,and human health.Several CYP450 subfamily genes are involved in the flavono...
关键词：SOYBEAN CYP82 CYP82D26 ISOFLAVONOIDS Enzymatic activity 
Molecular mechanisms of isoflavone puerarin against cardiovascular diseases:What we know and where we go被引量：5
《Chinese Herbal Medicines》2022年第2期234-243,共10页Weida Qin Jianghong Guo Wenfeng Gou Shaohua Wu Na Guo Yuping Zhao Wenbin Hou 
supported by the National Key Research and Development Program of China[Grant No.2017YFC1702901];Fundamental Research Funds for the central public welfare research institutes[Project No.JBGS2021002];China Academy of Chinese Medical Sciences(CACMS)innovation fund[Grant No.CI2021A05031]。
Puerarin(Pue),known as a phytoestrogen,has salient bioactivities and is promising against cardiovascular diseases.This article summarizes the underlying molecular mechanisms of Pue in treating cardiovascular diseases,...
关键词：cardiovascular disease molecular mechanism PUERARIN signaling pathways 
Molecular cloning and functional characterization of an isoflavone glucosyltransferase from Pueraria thomsonii
《Chinese Journal of Natural Medicines》2022年第2期133-138,共6页DUAN Hai-Yan WANG Jian ZHA Liang-Ping PENG Hua-Sheng ZHAO Yu-Ping YUAN Yuan HUANG Lu-Qi 
supported by the National Key Research and Development Program of China(Nos.2017YFC1702901 and 2017YFC1701601);CAMS Innovation Fund for Medical Sciences(No.2019-I2M-5-065)。
Pueraria thomsonii has long been used in traditional Chinese medicine.Isoflavonoids are the principle pharmacologically active components,which are primarily observed as glycosyl-conjugates and accumulate in P.thomson...
关键词：Flavonone ISOFLAVONE GLUCOSYLTRANSFERASE 4′-O-glucosylation 7-O-glucosylation 
Evaluation of Isoflavones as Allelochemicals with Strong Allelopathic Activities of Kudzu Using Protoplast Co-Culture Method with Digital Image Analysis被引量：1
《American Journal of Plant Sciences》2021年第3期376-393,共18页Kentaro Kobayashi Hamako Sasamoto Yutaka Sasamoto Akifumi Sugiyama Yoshiharu Fujii 
The inhibitory allelopathic activity of Pueraria montana (Kudzu), and activities of two putative allelochemical isoflav...
关键词：Allelopathy Bioassay DAIDZEIN ISOFLAVONE Protoplast Culture PUERARIN 
An isoflavone derivative potently inhibits the angiogenesis and progression of triple-negative breast cancer by targeting the MTA2/SerRS/VEGFA pathway被引量：6
《Cancer Biology & Medicine》2020年第3期693-706,共14页Xiaotong Zhang Gengyi Zou Xiyang Li Lun Wang Tianyu Xie Jin Zhao Longlong Wang Shunchang Jiao Rong Xiang Haoyu Ye Yi Shi 
This work was supported by grants from the National Natural Science Foundation of China(Grant Nos.81772974,81972882,and 81874297);the Bilateral Inter-Governmental S&T Cooperation Project from Ministry of Science and Technology of China(Grant No.2018YFE0114300);the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University.We thank Dr.Scott McKercher(The Scripps Research Institute,La Jolla,CA,USA);Dr.Phillip Bryant(Childrens Hospital of Philadelphia,PA,USA);Dr.Cameron R.McKay(Nankai University School of Medicine,Tianjin,China)for revising the manuscript.
Objective:Angiogenesis plays a vital role in tumor growth and metastasis.Here,we aimed to find novel efficient antiangiogenic molecules targeting vascular endothelial growth factor A(VEGFA)at the transcriptional level...
关键词：ISOFLAVONE MTA2 SERRS tumor angiogenesis VEGFA 
Isoflavones and inflammatory bowel disease被引量：7
《World Journal of Clinical Cases》2020年第11期2081-2091,共11页Ze-Yu Wu Li-Xuan Sang Bing Chang 
Supported by Innovative Talent Support Program of the Institution of Higher Learning in Liaoning Province,No.2018-478;Innovative Talents of Science and Technology Support Program of Young and Middle People of Shenyang,No.RC170446.
Isoflavones constitute a class of plant hormones including genistein,daidzein,glycitein,formononetin,biochanin A,and irilone,and the major source of human intake is soybeans.Inflammatory bowel disease(IBD)is a chronic...
关键词：ISOFLAVONE METABOLISM EFFECTS Inflammatory bowel disease STRUCTURE TREATMENT 
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