PIPERAZINE

作品数：67被引量：76H指数：4
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相关领域：理学更多>>
相关作者：王超陈之荣孙兰翁玲玲刘景生更多>>
相关机构：华中农学院中国医学科学院北京协和医学院福州大学北京大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Science China Chemistry》《Asian Journal of Pharmaceutical Sciences》《无机化学学报》更多>>
相关基金：国家自然科学基金天津市自然科学基金国家高技术研究发展计划国家重点基础研究发展计划更多>>
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Effect of Fluorine Atoms and Piperazine Rings on Biotoxicity of Norfloxacin Analogues:Combined Experimental and Theoretical Study
《Environment & Health》2024年第12期886-901,共16页Chuanxi Yang Xiaoning Wang Xinyan Zhao Yongkun Wu Jingyan Lin Yuhan Zhao Yiyong Xu Kaipeng Sun Chao Zhang Ziheng Wan Weihua Zhao Yihua Xiao Haofen Sun Dong Chen Wenping Dong Tieyu Wang Weiliang Wang 
To clarify the effect of the fluorine atom and piperazine ring on norfloxacin(NOR),NOR degradation products(NOR-DPs,P1−P8)were generated via UV combined with hydrogen peroxide(UV/H2O2)technology.NOR degradation did no...
关键词：NORFLOXACIN biotoxicity inhibition effect molecular docking structure−activity relationship 
Discovery of an enantiopure N-[2-hydroxy-3-phenyl piperazine propyl]-aromatic carboxamide derivative as highly selectiveα_(1D/1A)-adrenoceptor antagonist and homology modelling
《Chinese Chemical Letters》2024年第11期435-441,共7页Junjun Huang Ran Chen Yajian Huang Hang Zhang Anran Zheng Qing Xiao Dan Wu Ruxia Duan Zhi Zhou Fei He Wei Yi 
supported by Natural Science Foundation of Guangdong Province(Nos.2021A1515010101,2021A1515011372,2023A1515011895);National Natural Science Foundation of China(Nos.21807017,82273759,32371529);Guangzhou Medical University Scientific Research Capacity Improvement Project(No.02-410-2405104)。
α_(1)-Adrenergic receptor(AR)blockers can be effective for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms(BPH/LUTS),their usage is limited by cardiovascular-related side effects that are c...
关键词：Benign prostatic hyperplasia α_(1)-AR antagonist Phenylpiperazine Homology modelling Subtype selectivity 
Effect of the presence of trace sulfur dioxide on piperazine-based amine absorbents for carbon dioxide capture
《Chinese Journal of Chemical Engineering》2024年第9期34-41,共8页Songtao Zheng Yao Jiang Shaojun Jia Yan Wu Peng Cui 
supported by the Major Science and Technology Project of Anhui Province(201903a07020004);the National Natural Science Foundation of China(22208078);the Fundamental Research Funds for the Central Universities(JZ2023HGTB0226).
The effect of the presence of trace SO_(2)in industrial flue gas on the amine-scrubbing-based absorption process for CO_(2)capture has been a matter of concern.This study aimed to investigate the effect of trace SO_(2...
关键词：CO_(2)capture PIPERAZINE Amine absorbent Trace SO_(2) Absorption 
Piperazine-derived ionizable lipids for enhanced mRNA delivery and cancer immunotherapy
《Nano Research》2024年第8期7357-7364,共8页Kai Xu Yujia Xu Jin Sun Xinwei Cheng Chenxi Lu Wenzhong Chen Bingfang He Tianyue Jiang 
supported by the National Key Research and Development Program of China(No.2019YFA0905200);the National Natural Science Foundation of China(No.82072045);the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX23_1504).
Messenger ribonucleic acid(mRNA)-based therapeutics hold great prospects in disease treatment and lipid nanoparticles(LNPs)are the most extensively applied non-viral platform for RNA delivery in clinics.Despite the cl...
关键词：ionizable lipid lipid nanoparticle piperazine-derived lipid mRNA therapeutics cancer immunotherapy 
Piperazine-Assisted Construction of 2D/3D Wide-Bandgap Perovskite for Realizing High-Efficiency Perovskite/Organic Tandem Solar Cells
《Chinese Journal of Chemistry》2024年第16期1819-1827,共9页Ziyue Wang Shuaiqing Kang Xia Zhou Haiyang Chen Xingxing Jiang Zhichao Zhang Jialei Zheng Ruopeng Zhang Weijie Chen Jiandong Zhang Yaowen Li 
supported by the National Key Research and Development Program of China(Grant No.2022YFB4200302);the National Natural Science Foundation of China(Grant Nos.52325307,52203233,22075194,and 52273188);Department of Science and Technology of Jiangsu Province(No.BE2022023);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);Collaborative Innovation Center of Suzhou Nano Science and Technology,and the Key Laboratory of Polymeric Materials Design and Synthesis for Biomedical Function,Soochow University,Undergraduate Training Programfor Innovation and Entrepreneurship,Soochow University(No.202310285036Z).
Monolithic perovskite/organic tandem solar cells(TsCs)have gained significant attention due to their easy device integration and the potential to surpass the Shockley-Queisser limit of single-junction solar cells.Howe...
关键词：Perovskite/organic tandem solar cell Defect states Piperazine ion salt Energy conversion Low-dimensional materials Perovskitesolar cells 2D/3D perovskites Efficiency 
Piperazine:Its role in the discovery of pesticides被引量：1
《Chinese Chemical Letters》2023年第8期69-75,共7页Wei Zhang Shengxin Guo Lijiao Yu Ya Wang Yonggui Robin Chi Jian Wu 
The financial supports from National Natural Science Foundation of China(NSFC,Nos.32072445,21762012);the Program of Introducing Talents to Chinese Universities(No.D20023);the S&T Planning Project of Guizhou Province(No.[2017]5788);Graduate Research Fund in Guizhou Province(No.YJSKYJJ[2021]038).
Derivatives of piperazine,which is one of the most important heterocycles,are often used as linkers to connect active substructures that show promising bioactivities,especially in the field of agrochemicals.From 2000 ...
关键词：PIPERAZINE Innovation of pesticides ACTIVITY Research review Structure-activity relationship 
Optimized solubility and bioavailability of genistein based on cocrystal engineering
《Natural Products and Bioprospecting》2023年第1期450-463,共14页Zhipeng Wang Qi Li Qi An Lixiang Gong Shiying Yang Baoxi Zhang Bin Su Dezhi Yang Li Zhang Yang Lu Guanhua Du 
the National Natural Science Foundation of China(Grant No.22278443);CAMS Innovation Fund for Medical Sciences(Grant No.2022-I2M-1-015);the Chinese Pharmacopoeia Commission Drug Standard Promoting Fund(Grant No.2023Y11)for financial support.
With various potential health-promoting bioactivities,genistein has great prospects in treatment of a series of complex diseases and metabolic syndromes such as cancer,diabetes,cardiovascular diseases,menopausal sympt...
关键词：GENISTEIN PIPERAZINE COCRYSTAL SOLUBILITY BIOAVAILABILITY 
Polyamide Nanofiltration Membrane from Surfactant-assembly Regulated Interfacial Polymerization of 2-Methylpiperazine for Divalent Cations Removal
《Chemical Research in Chinese Universities》2022年第3期782-789,共8页GONG Li ZHU Yuzhang DONG Dianyu ZHANG Yuping GUI Liangliang JIN Jian 
This work was supported by the National Key Research and Development Program of China(No.2019YFA0705800);the National Natural Science Foundation of China(Nos.21988102,51873230);the National Natural Science Funds for Distinguished Young Scholars of China(No.51625306);the Youth Innovation Promotion Association of Chinese Academy of Sciences.
Removal of metal ions from water can not only alleviate the scaling problem of domestic and industrial water,but also solve the water safety problem caused by heavy metal ion pollution.Here,we fabricate a positively c...
关键词：Nanofiltration membrane Interfacial polymerization Surface charge Divalent cation removal 
Design, Synthesis, Crystal Structure and Photoluminescence Properties of Four New Europium (III) Complexes with Fluorinated β-Diketone Ligand
《Crystal Structure Theory and Applications》2021年第1期1-13,共13页Tetsuji Moriguchi Hiromasa Kawata Venkataprasad Jalli 
The strong photoluminescence properties of europium complexes with organic ligands attracted the attention of many researchers and found a wide range of uses in medical, industrial and biological fields. In this artic...
关键词：Tetrakis Europium Complexes Luminescence Fluorinate β-Diketone Ligand PYRIDINE BIPYRIDINE PIPERAZINE Bipiperidine 
Synthesis of N-Heterocyclic Carbine Silver(Ⅰ)and Palladium(Ⅱ)Complexes with Acylated Piperazine Linker and Catalytic Activity in Three Types of C-C Coupling Reactions
《Chinese Journal of Chemistry》2021年第3期605-613,共9页Qingxiang Liu Xiantao Zhang Zhixiang Zhao Xinying Li Wei Zhang 
the Tianjin Natural Science Foundation(No.18JCZDJC99600);the National Natural Science Foundation of China(No.21572159);the Program for Innovative Research Team in University of Tianjin(TD13-5074).
Main observation and conclusion Two bis-imidazolium salts LH_(2)·Cl_(2) and LH_(2)·(PF_(6))_(2) with acylated piperazine linker and two N-heterocyclic carbene(NHC)silver(Ⅰ)and palladium(Ⅱ)complexes[L_(2)Ag_(2)](PF...
关键词：SILVER PALLADIUM N-Heterocyclic carbine Catalytic actity C-C coupling reaction 
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