EPIRUBICIN

作品数：40被引量：116H指数：6
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相关领域：医药卫生更多>>
相关作者：吕万良刘磊居瑞军马莉莉林其敏更多>>
相关机构：北京大学陕西省肿瘤医院中山医学大学天津市肿瘤医院更多>>
相关期刊：《Journal of Hainan Medical University》《Current Medical Science》《Journal of Chinese Pharmaceutical Sciences》《Holistic Integrative Oncology》更多>>
相关基金：国家自然科学基金北京市自然科学基金国家重点基础研究发展计划上海市卫生局资助项目更多>>
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Clinical value of combining epirubicin with mindfulness intervention in patients with urinary system tumors and depression
《World Journal of Psychiatry》2025年第1期54-62,共9页Juan Liu Yan-Ping Guo Yan-Mei Lu Bei-Lin Wang 
BACKGROUND Urinary system tumors often cause negative psychological symptoms,such as depression and dysphoria which significantly impact immune function and indirectly affect cancer prognosis.While epirubicin(EPI)is r...
关键词：Urinary system tumor Bladder cancer Prostate cancer DEPRESSION EPIRUBICIN 
Branched glycopolymer prodrug-derived nanoassembly combined with a STING agonist activates an immuno-supportive status to boost anti-PD-L1 antibody therapy被引量：1
《Acta Pharmaceutica Sinica B》2024年第5期2194-2209,共16页Zhilin Li Qianfeng Zhang Zhiqian Li Long Ren Dayi Pan Qiyong Gong Zhongwei Gu Hao Cai Kui Luo 
This work was supported by National Natural Science Foundation of China(32271445,52073193,and 82202322);National Science and Technology Major Project of China(2023YFB3810004);1·3·5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYJC21013,China);the Sichuan Science and Technology Program(2023NSFSC1592,China),the China Postdoctoral Science Foundation(2021M692255,China);the Post-Doctor Research Project,West China Hospital,Sichuan University(2020HXBH094,China).
Despite the great potential of anti-PD-L1 antibodies for immunotherapy,their low response rate due to an immunosuppressive tumor microenvironment has hampered their application.To address this issue,we constructed a c...
关键词：GLYCOPOLYMER Polymer prodrug Immunogenic cell death Nanoassembly EPIRUBICIN STING pathway Immuno-supportive microenvironment Immunotherapy 
Efficacy and safety of short‑term intravesical gemcitabine vs.long‑term intravesical epirubicin in the treatment of moderate to high‑risk non‑muscle‑invasive bladder cancer:a pilot study
《Holistic Integrative Oncology》2024年第1期642-648,共7页Feiran Chen Jun Du Xusheng Chen Qing Yang Lei Diao Xin Yao 
Purpose Long-term bladder instillation therapy will bring more infusion side effects and economic consumption to patients.This study aims to compare short-term gemcitabine vs.long-term epirubicin for intravesical chem...
关键词：Efficacy EPIRUBICIN GEMCITABINE Intravesical therapy Non-muscle invasive bladder cancer 
Changes of protein expression during tumorosphere formation of small cell lung cancer circulating tumor cells
《Oncology Research》2023年第1期13-22,共10页SANDRA STICKLER BARBARA RATH MAXIMILIAN HOCHMAIR CLEMENS LANG LUKAS WEIGL GERHARD HAMILTON 
partially funded by the“Medical Scientific Fund of the Mayor of the City of Vienna”,Grant Number 21040 to Dr.C.Lang.
Small cell lung cancer(SCLC)is frequently disseminated and has a dismal prognosis with survival times of approximately two years.This cancer responds well to initial chemotherapy but recurs within a short time as a gl...
关键词：SCLC SPHEROID CHEMORESISTANCE EPCAM TOPOTECAN EPIRUBICIN 
Computational study of some potential inhibitors of COVID-19:A DFT analysis
《Quantitative Biology》2022年第4期341-350,共10页Prabhat Ranjan Kumar Gaurav Tanmoy Chakraborty 
We would like to thank Manipal University Jaipur and Sharda University for providing computational facilities and research support.
Background:There is an urgent demand of drug or therapy to control the COVID-19.Until July 22,2021 the worldwide total number of cases reported is more than 192 million and the total number of deaths reported is more ...
关键词：COVID-19 repurposing drug density functional theory HOMO-LUMO EPIRUBICIN APREPITANT 
Cepharanthine sensitizes human triple negative breast cancer cells to chemotherapeutic agent epirubicin via inducing cofilin oxidation-mediated mitochondrial fission and apoptosis被引量：1
《Acta Pharmacologica Sinica》2022年第1期177-193,共17页Li-wen Shen Xiu-xing Jiang Zhi-qiang Li Jie Li Mei Wang Guan-fei Jia Xin Ding Ling Lei Qi-hai Gong Ning Gao 
This work was supported by the National Natural Science Foundation of China(31571425;82004009);the grant from the“Hundred”Level of High-level Innovative Talents in Guizhou Province(QKHRCPT20165684);the Science and Technology Plan Program of Guizhou Province(2018,5772-071).We thank James Bamburg(University of Wisconsin)for providing Cofilin-WT and site mutant plasmids of cofilin(Cofilin-S3A and Cofilin-S3E).
Inhibition of autophagy has been accepted as a promising therapeutic strategy in cancer,but its clinical application is hindered by lack of effective and specific autophagy inhibitors.We previously identified cepharan...
关键词：triple negative breast cancer CEPHARANTHINE EPIRUBICIN mitochondrial superoxide oxidative stress COFILIN mitochondrial fission APOPTOSIS 
Discussion on the Efficacy and Safety of Epirubicin Injection Combined with Paclitaxel Liposome Injection and Carboplatin Injection in the Treatment of Cervical Cancer
《外文科技期刊数据库(文摘版)医药卫生》2021年第3期633-637,共5页LAI Yinglu LU Guang LI Keke QIAN Jiaen 
Objective: to explore the efficacy and safety of epirubicin injection combined with paclitaxel liposome injection and carboplatin injection in the treatment of cervical cancer. Methods: 68 cases of cervical cancer pat...
关键词：cervical cancer EPIRUBICIN paclitaxel liposome injection carboplatin injection 
Dose-dense paclitaxel plus carboplatin vs.epirubicin and cyclophosphamide with paclitaxel as adjuvant chemotherapy for high-risk triple-negative breast cancer被引量：4
《Chinese Journal of Cancer Research》2020年第4期485-496,共12页Qing Li Jiani Wang Yuxin Mu Tongtong Zhang Ying Han Jiayu Wang Qiao Li Yang Luo Fei Ma Ying Fan Pin Zhang Binghe Xulj 
This work was supported by National Key Research and Development Program of China(No.2O18YFC13121O1);Chinese Academy of Medical Science Initiative for Innovative Medicine(No.CAMS-2016-I2M-1-010).
Objective:The objective of this open-label,randomized study was to compare dose-dense paclitaxel plus carboplatin(PCdd)with dose-dense epirubicin and cyclophosphamide followed by paclitaxel(ECdd-P)as an adjuvant chemo...
关键词：Triple-negative breast cancer dose-dense adjuvant chemotherapy CARBOPLATIN PACLITAXEL 
Effectiveness of taxanes over anthracyclines in neoadjuvant setting:A systematic-review and meta-analysis
《World Journal of Meta-Analysis》2019年第4期170-183,共14页Mona Pathak Sada Nand Dwivedi SVS Deo Bhaskar Thakur Vishnubhatla Sreenivas Goura Kishor Rath 
BACKGROUND Anthracyclines and taxanes are more active group of chemotherapy regimen.Randomized controlled trials(RCTs) reported variable evidences regarding efficacy of taxanes over anthracyclines for tumor response a...
关键词：DOCETAXEL Paclitaxel EPIRUBICIN Doxorubicin Pathological complete response Breast CONSERVING surgery 
Docetaxel, cisplatin, and 5-fluorouracil compared with epirubicin,cisplatin, and 5-fluorouracil regimen for advanced gastric cancer:A systematic review and meta-analysis被引量：5
《World Journal of Clinical Cases》2019年第5期600-615,共16页Bo Li Lian Chen Hong-Liang Luo Feng-Ming Yi Yi-Ping Wei Wen-Xiong Zhang 
Supported by National Natural Science Foundation of China,No.81560345
BACKGROUND As the first-line regimens for the treatment of advanced gastric cancer, both docetaxel, cisplatin, and 5-fluorouracil(DCF) and epirubicin, cisplatin, and 5-fluorouracil(ECF) regimens are commonly used in c...
关键词：GASTRIC cancer Chemotherapy DOCETAXEL EPIRUBICIN CISPLATIN 5-FLUOROURACIL 
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