A Phase Ⅰ trial of dose escalation of topotecan combined with whole brain radiotherapy for brain metastasis in lung cancer  

拓普替康联合全脑照射肺癌脑转移的Ⅰ期临床试验(英文)

作　　者：Xiaohui Ge Wenyan Zhao Xiaocang Ren  Yongqiang Wang Zhigang Li Yanqi Li Yuee Liu Qiang Lin 

机构地区：[1]Department of Radiotherapy, Affiliated Hospital of Heibei University, Baoding 071000, China [2]Department of Oncology, Affiliated North China Petroleum Bureau General Hospital of Hebei Medical University,Renqiu 062552, China

出　　处：《The Chinese-German Journal of Clinical Oncology》2012年第8期449-451,共3页中德临床肿瘤学杂志（英文版）

摘　　要：Objective The aim of this study was to define the maximum-tolerated dose (MTD) and observe the toxicity of escalating topotecan combined whole brain radiotherapy for brain metastasis in lung cancer.

关 键 词：brain metastasis neoplasm/lung cancer TOPOTECAN RADIOTHERAPY CHEMOTHERAPY maximum tolerated dose 

分 类 号：R73[医药卫生—肿瘤]