Project supported by the National Natural Science Foundation of China(Grant Nos.11374234,11575128,11774272,and 11647312)
Nucleic acids are negatively charged biomolecules, and metal ions in solutions are important to their folding structures and thermodynamics, especially multivalent ions. However, it has been suggested that the binding...
supported by the National Basic Research Program of China(Grant No.2011CB933600);the National Natural Science Foundation of China(Grant Nos.11175132,11575128,and 11374234);the Program for New Century Excellent Talents,China(Grant No.NCET 08-0408)
The structural flexibility of nucleic acids plays a key role in many fundamental life processes, such as gene replication and expression, DNA-protein recognition, and gene regulation. To obtain a thorough understandin...
supported by the National Natural Science Foundation of China(Grant Nos.11074191,11175132,and 11374234);the National Basic Research Programof China(Grant No.2011CB933600);the Program for New Century Excellent Talents of China(Grant No.NCET 08-0408)
Many recent exciting discoveries have revealed the versatility of RNAs and their importance in a variety of cellular functions which are strongly coupled to RNA structures. To understand the functions of RNAs, some st...