国家自然科学基金(31100622)

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相关作者：李华雷国伟毛立明杨桂文孟广勋更多>>
相关机构：山东师范大学中国科学院上海巴斯德研究所更多>>
相关期刊：《中国细胞生物学学报》《Protein & Cell》更多>>
相关主题：NLRP3INFLAMMASOME炎症微生物感染天然免疫更多>>
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The NLRP3 Inflammasome activation in human or mouse cells,sensitivity causes puzzle
《Protein & Cell》2013年第8期565-568,共4页Hongbin Wang Liming Mao Guangxun Meng 
This work was supported by grants from 100 Talent Program of the Chinese Academy of Sciences,National Natural Science Foundation of China(Grant Nos.91029707,31170868,812111134,and 31100622);SASIBS Scholarship Program,Chinese Post-doctoral Science Foundation(No.20110490752);Post-doctoral research foundation of Shanghai Institutes for Biological Sciences(No.2011KIP513);the National Science and Technology Key Project(No.2012ZX10002007-003);as well as the CAS/SAFEA International Partnership Program for Creative Research Teams.
SIGNAL 1 ALONE IS ENOUGH TO ACTIVATE THE NLRP3 INFLAMMAOSME IN HUMAN CELLS According to our current understanding,the NLR family,pyrin domain containing 3(NLRP3)infl ammasome activation is generally a two-step process...
关键词：NLRP3 ACTIVATION CYTOKINES 
Pannexin-1 infl uences peritoneal cavity cell population but is not involved in NLRP3 infl ammasome activation
《Protein & Cell》2013年第4期259-265,共7页Hongbin Wang Yue Xing Liming Mao Yi Luo Lishan Kang Guangxun Meng 
supported by grants from 100 Talent Program of the Chinese Academy of Sciences,National Natural Science Foundation of China(Grant Nos.91029707,31170868,812111134,and 31100622);Shanghai Natural Science foundation(11ZR1442600);Novo Nordisk-CAS Research Foundation(NN-CAS-2010-5(SIBS));SASIBS Scholarship Program,Chinese Post-doctoral Science Foundation(20110490752);Post-doctoral research foundation of Shanghai Institutes for Biological Sciences(2011KIP513);grants for excellent scientist from Ministry of Human Resources and Social Security of China.
Pannexin-1(Panx1)forms nonselective large channel in cell plasma membrane and has been shown to be associated with NLRP3 inflammasome activation,ATP release and phagocytes recruitment.In the current study,by manipulat...
关键词：innate Immunity INFLAMMASOME NLRP3 Pannexin-1 PERITONITIS 
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