Acknowledgements This work was generously supported by the National Natural Science Foundation of China (Grant Nos. 81071454, 81171689 and 81301559), Department of Orthopedics Clinical Medical Centers in Jiangsu Province (BL2012004), the Natural Science Foundation of Jiangsu Province (BK20130275), and the Key Laboratory of Orthopedic Institute of Sooehow University.
To search for new bioactive materials which can be used as the substitute of bone repairing and drug carriers, Sema3A-Ioaded chitosan microspheres (SLCM) and silk fibroin (SF) were mixed with calcium sulfate ceme...