国家自然科学基金(21032002)

作品数：2被引量：1H指数：1
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相关期刊：《Chinese Journal of Chemistry》《Science China Chemistry》更多>>
相关主题：EMBEDMENTDERIVATIVESPOTENTTNF-HETEROCYCLE更多>>
相关领域：生物学化学工程环境科学与工程理学更多>>
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Synthesis and Absolute Configuration of Two Natural Phenolic Homobenzyl Esters
《Chinese Journal of Chemistry》2015年第7期729-738,共10页Murong Xu Shijun Zhu Zejun Xu Yikang Wu Po Gao 
This work was supported by the National Natural Science Foundation of China （21172247, 21032002） and the Chinese Academy of Sciences.
Two recently identified natural phenolic homobenzyl esters, isolated from Phragmipedium calurum （an orchid） and Eupatoriumfortunei TURCZ （a perennial herb in the Asteraceae family）, respectively, were synthesized ...
关键词：ESTERS ALKYLATION natural products STEREOCHEMISTRY PHENOLS 
Sinomenine derivatives with embedment of nitrogen-containing heterocycles exhibiting potent TNF-inhibitory activity被引量：1
《Science China Chemistry》2012年第12期2537-2547,共11页WANG Meng MA LiYan LOU YangTong BIAN Chao ZHOU TingTing ZHOU HaiBin LIAO HongZe MA Zhao YIN DongSheng CHEN AiZhong WANG ShaoZhong YANG ZhenYu SUN Bing YAO ZhuJun 
supported by the National Basic Research Program of China(973 Program,2010CB833200);National Natural Science Foundation of China(90713044,21032002);SHMCST (08431903000);the Fundamental Research Funds for the Central Universities(1082020502)
Inhibitory effect on tumor necrosis factor-c~ （TNF-c0 production by sinomenine derivatives with embedment of small drug-like nitrogen hetereocyclic moieties has been studied in this work. Several new sinomenine deriv...
关键词：SINOMENINE druggability HETEROCYCLE tumor necrosis factor-m inhibition 
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