国家自然科学基金(81201444)

作品数：4被引量：12H指数：3
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Improved Survival and Neurological Outcomes after Cardiopulmonary Resuscitation in Toll-like Receptor 4-mutant Mice被引量：5
《Chinese Medical Journal》2015年第19期2646-2651,共6页Li Xu Qing Zhang Qing-Song Zhang Qian Li Ji-Yuan Han Peng Sun 
This study was funded by the grants from the National Nature Science Foundation of China （No. 81201444, No. 81101401） and should be attributed to Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Background：Toll-like receptor 4 （TLR4） is a crucial receptor in the innate immune system and noninfectious immune responses.It has been reported that TLR4 participates in the pathological course of ischemia/reperfu...
关键词：Cardiac Arrest Cardiopulmonary Resuscitation Cerebral Injury Toll-like Receptor 4 
Minocycline Attenuates Microglial Response and Reduces Neuronal Death after Cardiac Arrest and Cardiopulmonary Resuscitation in Mice被引量：5
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2015年第2期225-229,共5页王黔艳 孙鹏 张清 姚尚龙 
supported by grants from the National Natural Science Foundation of China(No.81201444 and No.81101401)
The possible role of minocycline in microglial activation and neuronal death after cardiac arrest（CA） and cardiopulmonary resuscitation（CPR） in mice was investigated in this study. The mice were given potassium ch...
关键词：hippocampus neuronal microglia resuscitation operated histological immunosorbent saline hematoxylin administration 
Impact of Toll-like Receptor 4 Deficiency on Cerebrocardiac Syndrome被引量：3
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2014年第2期161-164,共4页孙鹏 徐丽 张清 李倩 
supported by the National Nature Science Foundation of China(No.81201444,No.81101401)
In order to investigate the role of Toll-like receptor 4 （TLR4） in cerebrocardiac syndrome （CCS）, the partial cerebral ischemia/reperfusion （I/R） models in mice with different TLR4 genotypes were established in ...
关键词：cerebrocardiac syndrome Toll-like receptor 4 myocardial tissue electron microscope 
Upregulated expression of S100A8 in mice brain after focal cerebral ischemia reperfusion
《World Journal of Emergency Medicine》2013年第3期210-214,共5页Peng Sun Qian Li Qing Zhang Li Xu Ji-yuan Han 
supported by grants from the National Nature Science Foundation of China(81201444 and 81101401)
BACKGROUND:Recent studies have showed that S100A8 has been implicated in the pathobiology of inflammatory disorders,and that cerebral ischemia reperfusion(l/R) rapidly activates inflammation responses via Toll-like re...
关键词：S100A8 Toll-like receptor 4 Cerebral ischemia reperfusion INFLAMMATION 
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