National Natural Sciences Foundation of China (Grant No. 90713005,20910094);the Ministry of Education of China (Grant No. 200800010078)
New cADPR mimic 5 that integrates the simplified nucleobase and ribose was designed and synthesized by using Cu(I)-catalyzed Huisgen [3+2] cycloaddition to build the simplified triazole nucleobase and microwave-ass...
National Natural Science Foundation of China (Grant No.20910094) ;Ministry of Education of China(Grant No.200800010078)
An optimized approach for the synthesis of N^1-ethoxymethyl-substituted cyclic inosine diphosphoribose(cIDPRE),an analogue of cyclic adenosine diphosphoribose(cADPR),has been developed via microwave-assisted intra...