National Natural Science Foundation of China (Grant No.20972099,31130017);Beijing Municipal Commission of Education (Grant No.KZ201210028035);Scientific Research Base Development Program of the Beijing Municipal Commission of Education;the 973 Project (Grant No.2013CB911000)
A novel series of compounds combining indolin-2-one and quinazolin-4(3H)-one moiety via a carbon-carbon double bond were synthesized by aldol-condensation of 2-methylquinazolin-4(3H)-one-6-carbaldehyde with variou...
was supported by the National Natural Science Foundation of China (No.31130017, 31071190, and 30711120570);the 973 project 2010CB911904;Funding Project for Academic Human Resources Development in Institutions of Higher Learning Under the Jurisdiction of Beijing Municipality (No. PHR20110508) to XX;the 973 project 2012CB911203 to YSC
DNA double-strand break(DSB) is the most severe form of DNA damage,which is repaired mainly through high-fidelity homologous recombination(HR) or error-prone non-homologous end joining(NHEJ).Defects in the DNA damage ...