国家自然科学基金(10774071)

作品数:7被引量:5H指数:1
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相关作者:章东龚秀芬张春兵邱媛媛郗晓宇更多>>
相关机构:南京大学江苏省中医院中国科学院北京源德生物医学工程有限公司更多>>
相关期刊:《物理学报》《Chinese Physics B》《声学学报》更多>>
相关主题:MICROBUBBLEMICROBUBBLES药物传递INFLUENCE细胞相互作用更多>>
相关领域:医药卫生理学更多>>
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Correlation between microbubble-induced acoustic cavitation and hemolysis in vitro
《Chinese Physics B》2011年第2期316-320,共5页张春兵 刘政 郭霞生 章东 
supported by the National Basic Research Program of China (Grant No. 2010CB732600);the National Natural Science Foundation of China (Grant Nos. 10774071,10974093,10974098,and 30672014);the Natural Science Foundation of Jiangsu Province of China (Grant NO. BE2010768);the Fund of the State Key Lab of Acoustics
Microbubbles promise to enhance the efficiency of ultrasound-mediated drug delivery and gene therapy by taking advantage of artificial cavitation nuclei. The purpose of this study is to examine the ultrasound-induced ...
关键词:acoustic cavitation passive cavitation detection MICROBUBBLES HEMOLYSIS 
Difference-frequency ultrasound generation from microbubbles under dual-frequency excitation被引量:1
《Chinese Physics B》2010年第9期437-442,共6页马青玉 邱媛媛 黄蓓 章东 龚秀芬 
supported by the National Natural Science Foundation of China (Grant Nos.10974098 and 10774071);the Natural Science Foundation of Jiangsu Province,China (Grant No.BK2009407);the Doctoral Foundation of Ministry of Education of China (Grant No.20093207120003);the National Basic Research Program of China (Grant No.2010CB732600)
The difference-frequency (DF) ultrasound generated by using parametric effect promises to improve detection depth owing to its low attenuation, which is beneficial for deep tissue imaging. With ultrasound contrast a...
关键词:difference-frequency MICROBUBBLE dual-frequency excitation parametric effect 
Finite element modeling of acoustic scattering from an encapsulated microbubble near rigid boundary
《Chinese Physics B》2010年第5期378-383,共6页黄蓓 张艳丽 章东 龚秀芬 
Project supported by the National Natural Science Foundation of China (Grant No. 10774071);the National Basic Research Prgram 973 (Grant No. 2010CB732600)from Ministry of Science and Technology,China;the Natural Science Foundation of Jiangsu Province,China (Grant No. BK2007518);the State Key Laboratory of Acoustics (Grant No. 200902)
This article proposes a finite element model (FEM) for predicting the acoustic scattering from an encapsulated microbubble near rigid boundary. The validity of the model is first examined by comparing the acoustic n...
关键词:bound encapsulated microbubble acoustic scattering finite element model 
Influence of the abdominal wall on the nonlinear propagation of focused therapeutic ultrasound被引量:2
《Chinese Physics B》2009年第11期4932-4937,共6页刘振波 范庭波 章东 龚秀芬 
Project supported by the Program for New Century Excellent Talents in University of China (Grant No 06-0450);the National Natural Science Foundation of China (Grant No 10774071);the Natural Science Foundation of Jiangsu Province, China (Grant No BK2007518)
This article theoretically studies the influence of inhomogeneous abdominal walls on focused therapeutic ultrasound based on the phase screen model. An inhomogeneous tissue is considered as a combination of a homogene...
关键词:phase aberration focused therapeutic ultrasound abdominal wall 
调频超声脉冲驱动微气泡运动偏移的研究被引量:1
《物理学报》2009年第7期4746-4751,共6页胡艺 葛云 章东 郑海荣 龚秀芬 
教育部新世纪优秀人才计划(批准号:06-0450);国家自然科学基金(批准号:10774071,30772070);江苏省自然科学基金(批准号:BK2007518)资助的课题;声场声信息国家重点实验室开放课题~~
提出调频超声辐射力技术驱动微泡群,以加强微泡的吸附效率.基于改进的RP方程及粒子轨迹方程研究了微泡群整体的运动位移与调频信号的中心频率、调频范围、信号声压,以及微泡半径分布关系.研究结果表明调频信号在驱动半径具有宽泛分布的...
关键词:超声辐射力 调频波 高斯分布 
超声增强脂质体与细胞相互作用的研究被引量:1
《物理学报》2009年第6期3996-4001,共6页张春兵 邱媛媛 郗晓宇 章东 
教育部新世纪优秀人才计划(批准号:NCET-06-0450);国家自然科学基金(批准号:10774071);江苏省自然科学基金(批准号:BK2007518)资助的课题~~
理论及实验研究了超声增强脂质体与细胞的相互作用.实验制作了包裹荧光素的脂质体,利用1MHz聚焦超声增强脂质体与乳癌细胞的相互作用,采用荧光显微镜观察与荧光素结合前后细胞的变化,流式细胞仪定量检测细胞中包含的荧光素.结果表明,在...
关键词:脂质体 药物传递 超声辐射力 
超声多普勒检测动脉内出血的多维度复合模型研究
《声学学报》2009年第1期24-29,共6页杨迪 章东 郭霞 龚秀芬 费兴波 
教育部新世纪优秀人才计划(06-0450);国家自然科学基金(10774071);江苏省自然科学基金(BK2007518)资助项目。
建立检测内出血点的量化技术有助于进一步提高超声止血的效率。提出了描述动脉血管内出血的多维度复合模型。由一个描述破裂血管的二维模型和一个描述下游血管系统响应的一维模型组成。计算机仿真及初步的活体实验结果证明了理论模型的...
关键词:超声多普勒 动脉血管 复合模型 快速检测 内出血 维度 血流速度 计算机仿真 
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