国家重点基础研究发展计划(2012CB917304)

作品数：2被引量：2H指数：1
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Genetic and environmental factors strongly influence risk,severity and progression of age-related macular degeneration
《Signal Transduction and Targeted Therapy》2016年第1期69-74,共6页Wenqiu Wang Katarzyna Gawlik Joe Lopez Cindy Wen Jie Zhu Frances Wu William Shi Samuel Scheibler Huimin Cai Ram Vairavan Alexander Shi Weldon Haw Henry Ferreyra Ming Zhang Sherman Chang Kang Zhang 
The study was partially supported by NSFC(81300778,81271020);973 program(2012CB917304);863 Program(2014AA021604);NIH(R01EY024134,R01HG008135,R01EY018660,R01EY021374)and VA Merit Award.
Age-related macular degeneration(AMD)is characterized by complex interactions between genetic and environmental factors.Here we genotyped the selected 25 single-nucleotide polymorphisms(SNPs)in 983 cases with advanced...
关键词：DEGENERATION prediction algorithm 
On the molecular mechanism of ion specific Hofmeister series被引量：2
《Science China Chemistry》2014年第1期36-47,共12页XIE WenJun LIU ChengWen YANG LiJiang GAO YiQin 
National Fund for Fostering Talents of Basic Sciences(J0630421);the National Natural Science Foundation of China(21125311);the National Basic Research Program of China(2012CB917304)for financial support
Hofmeister series ranks the ability of salt ions in influencing a variety of properties and processes in aqueous solutions.In this review,we reexamine how these ions and some other small molecules affect water structu...
关键词：Hofmeister series salt effects ion cooperativity hydrogen DONOR ACCEPTOR equilibrium surface tension protein dena-turant protein protectant 
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