国家自然科学基金(30772588)

作品数:1被引量:6H指数:1
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相关期刊:《Acta Pharmacologica Sinica》更多>>
相关主题:BRCA1/2THERAPEUTICSPOLYADP-RIBOSEAS更多>>
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Poly(ADP-ribose) polymerase inhibitors as promising :ancer therapeutics被引量:6
《Acta Pharmacologica Sinica》2010年第9期1172-1180,共9页Jin-xue HE Chun-hao YANG Ze-hong MIAO 
This work was supported by the grants from the National Natural Science Foundation of China (NSFC) (No 30772588 and No 30721005), the National Science & Technology Major Project"Key New Drug Creation and Manufacturing Program"of China (No 2009ZX09301-001) and the Science and Technology Commission of Shanghai Municipality (STCSM) (No 08DZ1980200).
The year of 2005 was a watershed in the history of poly(ADP-ribose) polymerase (PARP) inhibitors due to the important findings of selective killing in BRCA-deficient cancers by PARP inhibition. The findings made P...
关键词:poly(ADP-ribose) polymerase inhibitor DNA repair BRCA1/2 anticancer agents homologous recombination 
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